IMPORTANCE Scarring from bacterial keratitis remains a leading cause of visual loss. OBJECTIVE To determine whether topical corticosteroids are beneficial as an adjunctive therapy for bacterial keratitis if given early in the course of infection. DESIGN, SETTING, AND PARTICIPANTS The Steroids for Corneal Ulcers Trial (SCUT) was a randomized, double-masked, placebo-controlled trial that over...

BACKGROUND Epidural injection of corticosteroids is a commonly used treatment for radicular pain. However, the benefits are often short lived, and repeated injections are often limited secondary to concerns of side effects from cumulative steroid doses. In addition, rare, catastrophic complications, including brain and spinal cord embolic infarcts have been attributed to particulate steroid inj...

OBJECTIVE Despite the recommendation that patients with chronic lung diseases--many of whom receive corticosteroids--receive annual influenza vaccination, it is not known whether corticosteroids influence antibody response to influenza vaccine in this population. The purpose of this study was to assess whether patients with pulmonary conditions receiving long-term corticosteroid therapy develop...

This is a review of the medical literature regarding inhaled corticosteroids and their effects on growth and adrenal suppression in children and adolescents. A review of the literature, principally that published over the last five years, was conducted using Medline and searching indexes of articles published in national and international scientific journals. There is considerable controversy r...

Clinicians have generally avoided prescribing corticosteroids for active infection because of their known immunosuppressive effects and concern about long-term complications. We conducted a review of the published randomized, double-blind trials comparing corticosteroids and placebo in infections. Except in some trials of viral infections, sore throat, and cerebral cysticercosis, all patients a...

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Although allergic contact dermatitis (ACD) due to corticosteroids is a well-known and relatively common phenomenon, the systemic administration of corticosteroids only rarely produces skin reactions (systemic contact dermatitis [SCD]). We present the case of a patient with ACD to various corticosteroids, and who subsequently developed SCD to multiple systemic corticosteroids. A 47-year-old man ...

Background: This study was aimed to evaluate the orthopedists’ prescription pattern for outpatients referred to private clinics in Kerman province, Iran. Methods: In this study a total of 59,613 outpatients’ prescriptions issued by orthopedists contracting with Iran Health insurance organization and Iran Social Security Organization from the 1st May...

OBJECTIVE Topical corticosteroids and corticosteroid combinations are the principal treatments in psoriasis. The aim of this study was to investigate published literature dealing with medical adherence to topical corticosteroid or corticosteroid combinations in patients with psoriasis. MATERIALS AND METHODS Systematic electronic searches in English language literature were done until Septembe...