A detailed investigation has been made into the antiaromaticity and chemical reactivity of a planar cyclooctatetraene (COT) molecule fully annelated with bicyclo[2.1.1]hexane units 2. In spite of its planar 8pi-electronic structure, theoretical calculations have indicated that the antiaromaticity of COT 2 is considerably decreased in comparison with a planar COT 16 with D 4h symmetry. This beha...

Submarine nanorobots are being developed for use in branchy therapy, spinal surgery, cancer therapy, etc. Nanoparticles have been developed for use in drug delivery systems and for cure in eye disorders and for use in early diagnosis. Research in nanomedicine is under way in development of diagnostics for rapid monitoring, targeted cancer therapies, localized drug delivery, and improved cell ma...

Department of Chemistry, University at Alba NY 12222, USA. E-mail: mpetrukhina@alba Department of Chemistry, University of Wis Department of Biological and Chemical S Chicago, IL 60616, USA † Electronic supplementary information synthetic procedures, characterization crystallographic methods employed in th 1032188. For ESI and crystallographic dat DOI: 10.1039/c4sc03485f Cite this: Chem. Sci., ...

•Twisted rectangular subcomponents self-assemble into a large tetrahedral architecture•Each triangular face of the tetrahedron is composed three ligand units•A smaller M8L6 cubic assembly forms as an isolable kinetic intermediate•The host binds multiple equivalents dianionic guest Molecular capsules can catalyze reactions, perform chiral separations, and stabilize reactive molecules. Many molec...