The preparation and crystal structures of (4,11-dibenzyl1,4,8,11-tetraazabicyclo[6.6.2]hexadecaneN)copper(I) hexāuorophosphate, [Cu(C26H38N4)]PF6, and acetonitrile(4,11dibenzyl-1,4,8,11-tetraazabicyclo[6.6.2]hexadecaneN)copper(II) bis(hexa ̄uorophosphate), [Cu(C2H3N)(C26H38N4)](PF6)2, are described. The Cu I ion is tetracoordinated in a very distorted tetrahedron, while the Cu analogue is pentac...

The molecular mechanism of neurodegeneration in transmissible spongiform encephalopathies (TSEs) remains unclear. Using radioactive copper ((64)Cu) at physiological concentration, we showed that prion infected cells display a marked reduction in copper binding. The level of full-length prion protein known to bind the metal ion was not modified in infected cells, but a fraction of this protein w...

The present work is concerned to remove Cu using the biosorption potential of fungal biomass Aspergillus oryzae. The dry fungal biomass was used to optimize various parameters such as contact time, initial metal ion concentration, pH, biomass loading etc. A maximum of 91% Copper removal was observed in 5 mg/L initial Copper metal ion concentration using dry Aspergillus oryzae biomass. The perce...

Copper has many roles in biology that involve the change of coordination sphere and/or oxidation state of the copper ion. Consequently, the study of copper in heterogeneous environments is an important area in biophysics. EPR is a primary technique for the investigation of paramagnetic copper, which is usually the isolated Cu(II) ion, but sometimes as Cu(II) in different oxidation states of mul...

AIMS To compare silver and copper, metals with known antimicrobial properties, by evaluating the effects of temperature and humidity on efficacy by challenging with methicillin resistant Staphylococcus aureus (MRSA). METHODS AND RESULTS Using standard methodology described in a globally used Japanese Industrial Standard, JIS Z 2801, a silver ion-containing material exhibited >5 log reduction ...

Various non-spore forming bacteria, including Escherichia coli, enter a dormant-like state, the viable but non-culturable (VBNC) state, characterized by the presence of viable cells but the inability to grow on routine laboratory media. Upon resuscitation, these VBNC cells recover both culturability and pathogenicity. In 2011, a large outbreak involving more than 3000 cases of bloody diarrhoea ...

Copper binding to apolipoprotein B-100 (apo B-100) and its reduction by endogenous components of low-density lipoprotein (LDL) represent critical steps in copper-mediated LDL oxidation, where cuprous ion (Cu(I)) generated from cupric ion (Cu(II)) reduction is the real trigger for lipid peroxidation. Although the copper-reducing capacity of the lipid components of LDL has been studied extensivel...

Recently, genes for two copper-responsive regulatory systems were identified in the Escherichia coli chromosome. In this report, data are presented that support a hypothesis that the putative multicopper oxidase CueO and the transenvelope transporter CusCFBA are involved in copper tolerance in E. coli.

A novel stripping chemiluminescence (CL) method in situ has been developed which is a combination of selective stripping and CL detection in situ. This method consists of a concentration (pre-electrolysis) step, in which the analyte metal ion is reduced at a controlled potential whilst being deposited as the metal on a solid electrode placed in an electrogenerated chemiluminescence flow cell, a...

To remove heavy metals from aqueous solution and reclaim valuable materials from mushroom byproducts, Flammulina velutipes spent substrate (FVSS) was developed as a novel biosorbent for copper ion removal. Batch experiments demonstrated that ion removal was pH-, biosorbent dosageand initial metal concentration dependent. The maximum removal capacity of 15.56 mg/g was achieved at pH 6.0 with a b...