Current interests in the chemistry of high-nuclearity transition-metal complexes draw from their utility in the emerging science of nanomaterials, as models for the multimetal active sites of metal-storage proteins, and as single molecule magnets (SMMs). In addition, such super-sized molecules often show a variety of supramolecular interactions. The “self-assembly” process of generating a high-...

Electrospray ionization (ESI) mass spectrometry of methanolic solutions of mixtures of the copper salt (2,2′:6′,2′′-terpyridine)copper(II) nitrate monohydrate ([Cu(II)(tpy)(NO3)2]·H2O) and a tripeptide GXR (where X = 1 of the 20 naturally occurring amino acids) yielded [Cu(II)(tpy)(GXR)]•2+ ions, which were then subjected to collision induced dissociation (CID). In all but one case (GRR), these...

A set of four copper(ii) complexes, and (X = Cl, Br; = N-(l-leucine methyl ester)-N'-((2-pyridin-2-yl)methyl)oxalamide and = N-benzyl-N'-((2-pyridin-2-yl)methyl)oxalamide), have been synthesized and characterized by X-ray structural analysis, electron paramagnetic resonance (EPR) spectroscopy on single crystals and by SQUID magnetization measurements. X-ray diffraction studies show one-dimensio...

The title compound, [Cu(ClO(4))(2)(C(3)H(4)N(2))(4)], was obtained unexpectedly by the reaction of copper(II) perchlorate hexa-hydrate with equimolar amounts of 1-chloro-1-nitro-2,2,2-tripyrazolylethane in methanol solution. The crystal structure comprises octa-hedrally coordinated Cu(2+) ions, located on an inversion centre, with four pyrazole ligands in the equatorial plane. The average Cu-N ...

In the title compound, [Cu(2)Mn(C(5)HN(2)O(4))(2)(H(2)O)(6)](n), the Cu(II) ion is coordinated by two N atoms, two O atoms and one water O atom in a distorted square-pyramidal geometry. The Mn(II) ion is coordinated by two O atoms and four water O atoms in a distorted octa-hedral geometry. Two pyrazolyl-3,5-dicarboxyl-ate anions chelate to two copper ions, forming a dinuclear unit, which furthe...

Copper ions play an important role in ethylene receptor biogenesis and proper function. The copper transporter RESPONSIVE-TO-ANTAGONIST1 (RAN1) is essential for copper ion transport in Arabidopsis thaliana. However it is still unclear how copper ions are delivered to RAN1 and how copper ions affect ethylene receptors. There is not a specific copper chelator which could be used to explore these ...

Carmellose (CMC) is frequently used due to its high biocompatibility, biodegradability, and low immunogenicity for development of site-specific or controlled release drug delivery systems. In this experimental work, CMC dispersions in two different concentrations (1% and 2%) cross-linked by copper (II) ions (0.5, 1, 1.5, or 2.0 M CuCl₂) were used to prepare microspheres with antimicrobial activ...

The ability of 2,2'-bipyridine-bound copper(ii) ions to quench the photoluminescence of hydrophobic CdSe quantum dots is used to create a novel, selective turn-on fluorescence cyanide sensor.

The objectives of this and the following paper are to identify commonalities and disparities of the extended environment of mononuclear metal sites centering on Cu, Fe, Mn, and Zn. The extended environment of a metal site within a protein embodies at least three layers: the metal core, the ligand group, and the second shell, which is defined here to consist of all residues distant less than 3.5...

Data from cell culture and animal models of prion disease support the separate involvement of both heparan sulfate proteoglycans and copper (II) ions in prion (PrP) metabolism. Though direct interactions between prion protein and heparin have been recorded, little is known of the structural features implicit in this interaction or of the involvement of copper (II) ions. Using biosensor and enzy...