morphological changes in polyvinyl butyral (pvb) electrospun nanofibres can be acquired by preparation of pvb spinning solution in different solvents.  accordingly, three solvents, including ethyl alcohol, n-butanol and isopropanol, with diverse physical properties (e.g. boiling point, density, dipole moment and dielectric constant) were used to prepare polyvinyl butyral (pvb) spinning solution...

objective(s):the aim of this study was to prepare electrospun nanofibers of celecoxib using combination of time-dependent polymers with pectin to achieve a colon-specific drug delivery system for celecoxib. materials and methods:formulations were produced based on two multilevel 22 full factorial designs. the independent variables were the ratio of drug:time-dependent polymer (x1) and the amoun...

among the synthetic polymers, poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (phbv) microbial polyester is one of the biocompatible and biodegradable copolymers in the nanomedicine scope. phbv has key points and suitable properties to support cellular adhesion, proliferation and differentiation of nanofibers. nanofibers are noticeably employed in order to enhance the performance of biomaterials,...

Nanofibrous membranes, consisting of a poly(L-lactic acid) (PLLA)-silica xerogel hybrid material, were successfully fabricated from a hybrid sol using the electrospinning technique for guided bone regeneration (GBR) application. These hybrid nanofibers exhibited a homogeneous and continuous morphology, with a nano-sized dispersed silica xerogel phase in the PLLA fiber matrix. The mechanical pro...

With global concerns about the shortage of fossil fuels and environmental issues, the development of efficient and clean energy storage devices has been drastically accelerated. Nanofibers are used widely for energy storage devices due to their high surface areas and porosities. Electrospinning is a versatile and efficient fabrication method for nanofibers. In this review, we mainly focus on th...

Electrospinning in controlled nitrogen atmosphere is developed for the realization of active polymer nanofibers. Fibers electrospun under controlled atmospheric conditions are found to be smoother and more uniform than samples realized by conventional electrospinning processes performed in air. In addition, they exhibit peculiar composition, incorporating a greatly reduced oxygen content during...

In this article our latest advances in the development of efficient barrier systems against microand nano-particulate materials are presented. Nanofibrous polyamide 6 (PA6) mats were fabricated by electrospinning onto a nonwoven viscose substrate. The influence of electrospinning parameters including solution concentration, viscosity, and conductivity, were studied for the production of nonwove...

This chapter deals with an overview of design and fabrication of three-dimensional (3D) scaffolds for tissue engineering (TE) applications using the electrospinning technique. A general introduction to cellulose, a short overview of sources and methodology for the production of cellulose nanocrystals (CNCs), and principles of tissue engineering and the electrospinning technique will be given. A...

A fast discrete model for the simulations of thin charged jets produced during the electrospinning process is derived, based on an efficient implementation of the boundary element method for the computation of electrostatic interactions of the jet with itself and with the electrodes. Short-range electrostatic forces are evaluated with slender-body analytical approximations, whereas a hierarchic...

Nanoscale three-dimensional (3D) scaffolds offer great promise for improved tissue integration and regeneration by their physical and chemical property enhancements. Electrospinning is a versatile bottom-up technique for producing porous 3D nanofibrous scaffolds that could closely mimic the structure of extracellular matrix. Much work has been committed to the development of this process throug...