AIM The aim of this study was to evaluate factors affecting the risk for reexcision following breast-conserving surgery. Positive tumor margins are critical for local disease control following surgery for breast cancer. Several factors, including tumor size, multifocality, and an extensive in situ component, may be associated with a higher rate of repeat operations due to positive margins. This...

BACKGROUND Adjuvant radiotherapy after breast-conserving surgery is indicated in the vast majority of breast cancer patients. Conventionally fractionated radiotherapy with 50 Gy in 25 fractions was considered standard of care for several decades. The recently publishes long-term results of randomized trials that have tested different moderately hypofractionated radiotherapy schedules that may c...

Accounting for less than 1% of all breast cancer cases, male (MBC) is a rare disease. Unlike female cancer, there are no randomized controlled trials to confirm the safety breast-conserving surgery (BCS). Additionally, patients have poor radiation therapy (RT) compliance after BCS, which raises concern about curative treatment this patients. Therefore, BCS used in these The authors report case ...

Objectives: Breast conserving surgery (BCS) for early breast cancer is now an accepted treatment, but there are controversies about its comparability with mastectomy. Thus, we investigated the survival outcomes who underwent BCS and modified radical mastectomy (MRM). Methods: In this retrospective review, we analyzed the survival outcomes of 618 patients with early breast cancer who underwent t...

Objective: To help physicians and their patients arrive at optimal strategies for breast radiation therapy after breast-conserving surgery (BCS) for early breast cancer. Outcomes: Local control, survival, quality of life, adverse effects of irradiation and cosmetic results. Evidence: A literature search using MEDLINE from 1966 to October 2001 and CANCERLIT from 1983 to September 2001. A nonsyst...