background: although numerous studies have found deleterious effects of inbreeding on childhood and pre-reproductive mortality, one question remains inadequately addressed: dose inbreeding lead to increased childhood mortality rates in countries with high level of consanguinity? methods: to evaluate the public health impact of inbreeding on offspring mortality, the association between mean of i...

background: essential hypertension tends to a familial mode. its pattern of inheritance is heterogeneous, but the frequencies of different mode of inheritance vary in different populations. determining of the mode of inheritance in each family is the basic information that is needed for the risk estimation in those family members. determination of pattern of inheritance in families with at leas...

Consanguinity is an important problem in medical genetics because it significantly influences morbidity risks for recessive disorders. Genetic counsellors manage this problem in very simple terms according to Mendelian rules but without considering the theory of inbreeding in full. Consequently, the severity of specific recessive genetic risks is not accurately estimated. The purpose of this pa...

BACKGROUND Deafness is the hidden disability of childhood, and leads to poor educational and employment prospects. There is little published information on deafness in Pakistan. Profound hearing impairment is more prevalent in countries where consanguineous marriages are common, such as Pakistan. This study aimed to assess causes of childhood deafness and association with parental consanguinity...

objectives: the prevalence of consanguineous marriage is about 30 % in iran and this can increase the probability of incidence of genetic impairments such as hearing impairments. hearing impairment in comparison with other hereditary disorders is the most incident. the purpose of this survey is to identify the prevalence of consanguinity among the parents of sensoryneural hearing impaired stude...

a total of 8641 married couples were investigated from 28 iranian populations for consanguineous marriages and coefficient of inbreeding. the results showed considerable differences in the rate and kind of consanguineous matings among the various urban, rural, tribal, and religious populations studied. the observed frequencies of the consanguineous matings in the populations of iran are higher ...

Consanguineous marriages are respected and practiced among more than one billion of the world’s populationwith consanguinity rates reaching 20–50%. Consanguinity increases risk congenital anomalies, autosomalrecessive disorders, perinatal antenatal morbidities. This study determines knowledge regardingconsanguineous its genetic effects young adults.Objectives: 1. To assess regarding consanguine...

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system, immune origin. The aim this work was to study epidemiology and clinical parameters MS patients establish association between familial consanguinity. A retrospective conducted on medical records 129 with diagnosed at Neurology department Tlemcen UHC, in order determine epidemiological profile biological cha...