Conjunctival tumors are one of the most frequent tumors of the eye and adnexa. They comprise a large variety of conditions, from benign lesions such as papilloma to malignant lesions such as epidermoid carcinoma or melanoma which may threaten visual function and patient ́s life if not diagnosed early. Although conjunctival tumors may arise from any type of the conjunctival cells, epithelial and ...

INTRODUCTION Melanoma is a rare malignant tumour in the eye. OBJECTIVE To report two cases of malignant melanoma in the eye, one in the conjunctiva and the other in the choroid. CASES The first case was in a 49-year-old lady who presented with a swelling on the inner side of left upper eyelid. The vision was 6/6. On everting the eyelid, multiple, pigmented, nodular swellings were noted on t...

appear to bind copper in these disease states but are not known to do so in vitro. In at least 1 case, the coppercarrying protein was sequenced in an attempt to determine whether it shared the N-terminal Asp-Ala-His amino acid sequence known to bind copper in albumin, but no such sequence was found. Sequences as simple as Gly-His are capable of binding copper under certain circumstances, especi...

A 50‐year‐old woman presented with a brownish‐black inferior limbal mass for many years with rapidly increasing in size and encroaching on the cornea of the right eye over the past year. The clinical examination revealed a dark brown, elevated and irregular mass adhering to the underlying sclera and cornea with four feeder vessels [Figure 1a]. The mass had a maximum basal diameter of 8.0 mm and...

PURPOSE Conjunctival melanoma (CM) is an ocular malignancy with a high rate of local recurrences after treatment, and can give rise to deadly metastases. The establishment of a murine model will further our understanding of this disease and allow in vivo testing of new therapies. We therefore analyzed the ability of three CM cell lines to grow orthotopically and spread to distant sites. Further...

Impression cytology using cellulose acetate paper has been used in various ocular surface disorders as a simple non-invasive diagnostic test. To assess its value in differentiating melanocytic tumours, 24 patients with a range of pigmented lesions of the conjunctiva were examined using this technique. Cytological and histological diagnoses were compared in 23 cases. In 73% of cases impression c...

The Corresponding Author has the right to grant on behalf of all authors and does grant on behalf of all authors, an exclusive licence on a worldwide basis to the BMJ Publishing Group Ltd and its Licensees to permit this article (if accepted) to be published in BJO and any other BMJPGL products to exploit all subsidiary rights, as set out in our licence Abstract Background: To evaluate whether ...

absract intracranial invasion of cellular blue nevus (cbn) from the skin is extremely rare and such a condition with malignant transformation is even rarer. a case of meningeal melanoma with malignant transformation which was derived from an ota nevus is presented in this report. a21-year-old man with a neurocutaneous syndrome since childhood was referred with headache and mild left hemiparesia...

PURPOSE To evaluate risk factors for local recurrence, regional and distant metastases, and mortality associated with conjunctival melanoma. METHODS This was a retrospective study of 194 patients with histologically confirmed conjunctival melanoma diagnosed between 1950 and 2002 in the Netherlands. Data were collected from all university centers and many nontertiary hospitals, using the Natio...

Purpose To evaluate the prognosis in Chinese patients with conjunctival melanoma and determine its predictors. Further, to explore the racial differences in clinical characteristics and outcomes between Chinese and Caucasian patients. Methods This cohort study included 57 eyes of 57 consecutive patients with pathologically verified conjunctival melanoma between 1996 and 2016. Medical records ...