Background: Congenital hearing loss delays many aspects of a child's development, including speech and socio-cognitive development. The aim of this study was determine the results of infant hearing screening with transient evoked otoacoustic emission (TEOAE) in Moradi Hospital, Rafsanjan, Iran: 2014. Materials and Methods: In this descriptive cross-sectional study from 6017 infants born in Nik...

background hearing loss is the most common congenital disorder the incidence of which is further increased in the presence of risk factors for hearing loss among newborns admitted to the neonatal intensive care unit (nicu). the aim of this study was early diagnosis and intervention for hearing loss in newborns discharged from nicu. materials and methods this prospective cohort study was conduct...

Congenital hearing loss with many genetic and environmental causes affects 1 in 1000 newborns. Mutations in the GJB2(Gap Junction Beta-2) gene encoding the gap junction protein connexin 26 have been established as the main cause of autosomal recessive non-syndromic hearing loss. The aim of this study was to study the frequency of one mutation (35delG) of GJB2 gene in Kerman non-syndromic deaf p...

Hereditary hearing loss (HHL) comprises half of the congenital deafness which arises from genetic mutations. Mutations in the TJP2 gene, encoding tight junction protein 2, are one of the gene alterations in HHL resulting in an autosomal dominant nonsyndromic form of the disease. An 11-year-old male patient with clinically approved congenital hearing loss was referred to our laboratory....

People with hearing loss represent one of the largest disability groups worldwide, and the prevalence of hearing loss is predicted to rise with an ageing population. Substantial progress has been made towards understanding some of the biological processes involved in the development of hearing impairment as well as therapeutic ways to prevent or mitigate the hearing loss. For example, we now ha...

Manipulations of the sensory environment typically induce greater changes to the developing nervous system than they do in adulthood. The relevance of these neural changes can be evaluated by examining the age-dependent effects of sensory experience on quantitative measures of perception. Here, we measured frequency modulation (FM) detection thresholds in adult gerbils and investigated whether ...

Waardenburg syndrome is a known autosomal dominant cause of congenital hearing loss. It is characterized by a distinctive phenotypic appearance and often involves sensorineural hearing loss. Temporal bone abnormalities and inner ear dysmorphisms have been described in association with the disease. However, middle ear abnormalities as causes of conductive hearing loss are not typically seen in W...