Enzymes are biodegradable catalysts naturally present in living organisms. can accelerate biochemical reactions by reducing the activation energy, and they not consumed during reaction processes. Numerous applications of enzymes have been developed biotechnology, industry, medicine, pharmaceuticals, food processing, biofuels, so on. In this study, we develop a mathematical model describing enzy...

Inosinic acid dehydrogenase was partially purified from sarcoma 180 cells. The concentrations of each reactant, inosine 5’-phosphate, nicotinamide adenine dinucleotide, and K+, altered both the apparent K, and Vmaxvalues for each of the other reactants. Enzymatic activity was inhibited by both products of the reaction, xanthosine S-phosphate and reduced nicotinamide adenine dinucleotide; the in...

The basic biochemistry of the inhibition of cytochrome oxidase by NO is reviewed. Three possible mechanisms that include the binding of NO to the fully reduced Fe(a3)-Cu(B) site, to the semi-reduced Fe(a3)-Cu(B) site, and to the fully oxidized Fe(a3)-Cu(B) site are confronted with the experimental data. Mathematical models are used to facilitate the analysis and to solve puzzling observations c...