A comparative analysis of molecular genetic phenotypes mucous membrane cells in five anatomical regions the colon a group healthy donors was conducted by comparing mRNA expression profiles 62 genes involved regulation vital cellular function. We used 181 biopsy samples morphologically unchanged colonic mucosa, obtained from (ascending, transverse-colon, descending, sigmoid) and rectum sections ...

Background & Objective: The role of synchronized expression pattern of cytokeratin (CK) 7 and CK20 in the prognosis of colon adenocarcinoma is unclear. The current study aimed at determining the relationship between the expression of cytokeratins 7 and 20 and prognostic factors in colon adenocarcinoma. Methods: In the current cr...

Background: Colorectal cancer is a common cancer and has a high rate of mortality and morbidity. This can be reduced by screening tests. Some of the studies have recently referred to Red Cell Distribution Width (RDW) as a marker for early detection of various cancers. The aim of this study was to investigate the RDW and early detection of colorectal cancer and polyp. M...

the most common metastatic sites for colorectal carcinomas include the liver, lungs, brain, bones and peritoneal surfaces. in this report, a case of sigmoid colon carcinoma presented with cervical lymphadenopathy was detected with the help of pet/ct. a 57 year-old male presented with a complaint of swelling on the left side of his neck. ultrasonographic examination of the neck revealed three hy...

background geographic information system (gis) software has been used in health care systems to display and analyze spatial pattern of diseases and health services. objectives this study was performed to assess spatial patterns of colon’s pathologic lesions based on the pathologic reports and assess whether it is possible to use gis software in health services. patients and methods archives of ...

soybean isoflavone genistein has multiple anticancer properties and its pro-apoptotic and anti-proliferative effects have been studied in different cancer cells. however, the mechanisms of action of genistein and its molecular targets on human colon cells have not been fully elucidated. therefore, caspase-3 and p38 mitogen-activated protein kinase (p38 mapk) as the main therapeutic targets were...

postpolypectomy bleeding and perforation are the major complications of colonoscopy. this report presents a rare case of colon obstruction immediately after colonoscopy. a 56-year-old man underwent colonoscopy because of 6 months lower abdominal pain. colonoscopy revealed diverticulosis and multiple small sessile polyps in sigmoid colon. biopsy samples were taken from the polyps and the procedu...