INTRODUCTION Rats and mice have been used to evaluate effects of natural and synthetic oestrogens. However, data about oestrogen's effects on haemostasis in rodents is very limited. The aim of this work was to standardize blood coagulation screening tests in adult male, female, and ovariectomized (Ovx) Wistar rats and CD1 mice in an effort to evaluate the influence of gender and species differe...

Purpose: Many investigations indicate the direct and indirect effects of pineal gland on coagulation system particularly on thrombin time. It is well known that exhaustive exercise alters blood coagulation and fibrinolysis, but the assessment of the dimension and importance of these changes is difficult. This study was designed to determine the effect of physical activity interaction epiphysect...

We study a critical case of coagulation-fragmentation equations with multiplicative coagulation kernel and constant fragmentation kernel. Our method is based on the viscosity solutions to new singular Hamilton-Jacobi equation, which results from applying Bernstein transform original equation. include well-posedness, regularity, long-time behaviors equation in certain regimes, have implications ...

BACKGROUND Thromboelastometry (ROTEM(®)) might be useful to detect intraoperative coagulation disorders early in major paediatric surgery. This observational trial compares this technique to standard coagulation tests. METHODS Intraoperative blood sampling was obtained in children undergoing elective major surgery. At each time point, standard coagulation tests [activated partial thromboplast...

We present a methodology for personalizing the clinical treatment of severely injured patients with acute traumatic coagulopathy (ATC), an endogenous biological response of impaired coagulation that occurs early after trauma and shock and that is associated with increased bleeding, morbidity, and mortality. Despite biological characterization of ATC, it is not easily or rapidly diagnosed, not a...

Blood coagulation is the clotting and subsequent dissolution of the clot following repair to the damaged tissue. However, inducing blood coagulation is difficult for some patients with homeostasis dysfunction or during surgery. In this study, we proposed a method to develop an integrated system that combines optical coherence tomography (OCT) and laser microsurgery for blood coagulation. Also, ...

BACKGROUND The evacuated hemothorax has been poorly described because it varies with time, it has been found to be incoagulable, and its potential effect on the coagulation cascade during autotransfusion is largely unknown. METHODS This is a prospective descriptive study of adult patients with traumatic chest injury necessitating tube thoracostomy. Pleural and venous samples were analyzed for...

Introduction The coagulation cascade is a dynamic process dependent on many factors. It involves interaction between primary hemostasis, platelet clot formation, secondary hemostasis, thrombin generation, and fibrinolysis. The assessment of this process is particularly important in the surgical patient to properly assess patient coagulation assessment, manage hemostatic therapy and transfusion ...