purpose this study was performed to determine the possible causes and mechanisms of fatalities among iranian mountaineers during climbing. methods by contacting several sources, deceased mountaineers were identified. data about the causes and mechanism of death was retrospectively obtained using a standard questionnaire for each case. results a total of 29 deaths were identified from march 2006...

Several haemostatic factors have been associated with incident arterial cardiovascular disease in prospective studies and meta-analyses. Plasma fibrinogen shows a strong and consistent association with risk; however, this may reflect its inflammatory marker status, and causality remains to be proven. The common haemostatic gene polymorphisms for factor II, factor V and the von Willebrand factor...

Coagulation factor replacement can effectively treat or prevent most hemophilia complications, but it is expensive. Although published data describe how to achieve therapeutic goals through cost-effective selection and dosing of replacement products, criteria are not universally known or followed. A review of our institution’s experience revealed overdosing of coagulation factors in the majorit...

Patients with diabetes mellitus are at increased risk of cardiovascular morbidity and mortality. Atherothrombosis, defined as atherosclerotic lesion disruption with superimposed thrombus formation, is the most common cause of death among these patients. Following plaque rupture, adherence of platelets is followed by local activation of coagulation, the formation of a cross-linked fibrin clot an...

PURPOSE OF REVIEW To critically appraise recent published literature about factors associated with cancer risk likely to be influenced by combination antiretroviral therapy (cART) in HIV-infected individuals, and the potential of earlier cART initiation to reduce this risk. RECENT FINDINGS Factors leading to increased risk of non-AIDS-defining malignancies (NADMs) in particular remain poorly ...

BACKGROUND Patients with end-stage liver disease (ESLD) are assumed to be at high risk of bleeding when undergoing any kind of invasive intervention (any kind of operation, including transplantation or minimally invasive interventions). Both bleeding and thrombosis are associated with a poor outcome. METHODS A selective literature research was conducted with the following key words: 'cirrhosi...

The focus of most previous research concerning tardive dyskinesia has been on the impact of risk factors on the development( incidence) of this syndrome. In this paper, we report our results on the relationship between risk factors and the severity of tardive dyskinesia. A total of 33 patients diagnosed as tardive dyskinesia with no other medical illness studied: 21 males and 12 females with a ...

introduction: in addition to the annual mortality rate, unintentional home injury may result in temporary or permanent disability and requires medical attention and continuous care in millions of children. this study aimed to explore features and risk factors of these injuries. methods: in this cross-sectional study, demographic variables and epidemiologic pattern of home injuries among childre...

Purpose: The study investigated the rate of complications associated with sonographically guided lymph node biopsies and assessed potential risk factors. Methods: A total of 536 sonographically guided puncture procedures (283 males, 52.8%; 253 females, 47.2%; average age 57.0 ± 16.0 years; range 14 87 years) were performed in 469 patients for the work-up of unclear lymphadenopathy. Events, comp...