نتایج جستجو برای: coa decarboxylase

تعداد نتایج: 35920  

Journal: :Plant Cell Tissue and Organ Culture 2021

Long-term subculture plays an essential role in the large-scale multiplication and production of somatic plantlets. We investigated effects long-term on vitro shoot development ex rooting associated with changes hormones protein profiles Cedrela fissilis. The number subcultures shoots induced a decrease response. reduction adventitious root (AR) formation was decreases contents indole-3-acetic ...

Journal: :Journal of Medicinal Chemistry 2021

Propionic acidemia (PA) and methylmalonic (MMA) are rare autosomal recessive disorders of propionyl-CoA (P-CoA) catabolism, caused by a deficiency in the enzymes P-CoA carboxylase methylmalonyl-CoA (M-CoA) mutase, respectively. PA MMA classified as intoxication-type inborn errors metabolism because intramitochondrial accumulation P-CoA, M-CoA, other metabolites results secondary inhibition mult...

2015
A Joe Shaw Bethany B Miller Stephen R Rogers William R Kenealy Alex Meola Ashwini Bhandiwad W Ryan Sillers Indraneel Shikhare David A Hogsett Christopher D Herring

BACKGROUND The liberation of acetate from hemicellulose negatively impacts fermentations of cellulosic biomass, limiting the concentrations of substrate that can be effectively processed. Solvent-producing bacteria have the capacity to convert acetate to the less toxic product acetone, but to the best of our knowledge, this trait has not been transferred to an organism that produces ethanol at ...

2016
Kanchana R Kildegaard Niels B Jensen Konstantin Schneider Eik Czarnotta Emre Özdemir Tobias Klein Jérôme Maury Birgitta E Ebert Hanne B Christensen Yun Chen Il-Kwon Kim Markus J Herrgård Lars M Blank Jochen Forster Jens Nielsen Irina Borodina

BACKGROUND In the future, oil- and gas-derived polymers may be replaced with bio-based polymers, produced from renewable feedstocks using engineered cell factories. Acrylic acid and acrylic esters with an estimated world annual production of approximately 6 million tons by 2017 can be derived from 3-hydroxypropionic acid (3HP), which can be produced by microbial fermentation. For an economicall...

Journal: :American journal of physiology. Heart and circulatory physiology 2004
Margaret P Chandler Janos Kerner Hazel Huang Edwin Vazquez Aneta Reszko Wenjun Z Martini Charles L Hoppel Makoto Imai Sharad Rastogi Hani N Sabbah William C Stanley

Recent human and animal studies have demonstrated that in severe end-stage heart failure (HF), the cardiac muscle switches to a more fetal metabolic phenotype, characterized by downregulation of free fatty acid (FFA) oxidation and an enhancement of glucose oxidation. The goal of this study was to examine myocardial substrate metabolism in a model of moderate coronary microembolization-induced H...

Journal: :Nature communications 2015
Ashley R Jurado Christine S Huang Xing Zhang Z Hong Zhou Liang Tong

Geranyl-CoA carboxylase (GCC) is essential for the growth of Pseudomonas organisms with geranic acid as the sole carbon source. GCC has the same domain organization and shares strong sequence conservation with the related biotin-dependent carboxylases 3-methylcrotonyl-CoA carboxylase (MCC) and propionyl-CoA carboxylase (PCC). Here we report the crystal structure of the 750-kDa α6β6 holoenzyme o...

Background Aortic Coarcatation (CoA) is one of the congenital heart diseases with the rate of 5-8% of Coronary heart diseases(CHDs). Balloon angioplasty is now one of the effective way of treatment for CoA, native or Re-coarctation (Re-CoA). We aimed to assess the immediate, and short term response to angioplasty and stenting, and also complications. Materials and Methods Balloon angioplasty wi...

Journal: :Journal of bacteriology 1955
J B WOLFE D IVLER S C RITTENBERG

It was previously shown that oxygen uptake per mole of substrate, using resting cell suspensions of a strain of Pseudomonas fluorescens, was significantly higher on malonate than on acetate (Wolfe and Rittenberg, 1953). If malonate is anaerobically decarboxylated to carbon dioxide and acetate, one would expect comparable oxygen consumption on the two substrates. The observed difference in uptak...

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