It was a pleasure and an honour to be invited to participate in this year’s CSCI symposium “Clinician Investigators: Pathway to Future Success”. Looking out into the audience, it was satisfying to see the room filled with so many trainees representing the various MD/PhD and CIP programs across Canada. As the first female graduate of University of Toronto’s MD/ PhD program, it was also very enco...

Drawing on literature from other professions, this paper identifies factors that occupational therapists should consider when making the transition from clinician to academician. It describes the following four stages of a professional career: apprentice, colleague, mentor, and sponsor. Five academic stages offaculty development are also presented. In addition, the work life of a faculty member...

At the core of all clinical dental practice is the interpersonal interaction between dentist and patient. An expansion of the dentist's responsibility in the unique dentist-patient relationship is suggested. Such an expanded role encourages dentists to engage the emotional and behavioral health of dental patients who are appearing in dental offices for treatment of orofacial diseases and other ...

pected disease is common or not, and whether the findings tend to support or discount this hypothesis. Such intuitive procedures may be, and often are, seriously biased1. It would be preferable to employ an open system where all the assumptions about diagnostic reasoning, and the way in which they are combined, are made quite explicit. Bayes theorem2 provides such a model. An understanding of h...

Acute myeloid leukemia (AML) is a heterogeneous disease, characterized by frequent resistance to available chemotherapeutic agents. The basic therapy for patients with AML has changed little over the past 30 years. Improvements in outcome in recent decades in younger adult cohorts have generally been ascribed to better supportive care (ie, transfusion and antimicrobial therapy); older adults wi...

Richard Platt, MD, MS, Harvard Pilgrim Health Care Institute, Harvard Medical School; Kathleen Blake, MD, MPH, American Medical Association; Patricia Franklin, MD, MBA, MPH, University of Massachusetts Medical School; J. Michael Gaziano, MD, MPH, VA Boston Healthcare System/Brigham and Women’s Hospital/Harvard Medical School; Robert Harrington, MD, Stanford University; Adrian Hernandez, MD, MHS...

Deficiency of insulin brings about rapid metabolic decompensation, but in several clinical states its action appears to be inadequate despite normal or raised serum concentrations of immunoreactive insulin. These insulin resistant states are characterised by raised circulating insulin concentrations in the face of normal or raised blood glucose concentrations. Table I lists some examples. Many ...

Because healthcare faces challenges, such as ensuring quality and access and controlling cost, effective leadership is needed at every level of healthcare organizations. Yet, physicians are trained in clinical and scientific skills but not in leadership competencies. Furthermore, clinicians often feel ill-prepared to assume managerial and leadership roles. To close this gap, training in leaders...

Ischemic preconditioning is a physiologic phenomenon that occurs in the cardiac muscle in which brief episodes of ischemia protect the heart when exposed to a sustained ischemia. Clinical counterparts include potential benefits of preinfarction angina and less ischemia after a second, compared to a first, coronary angioplasty balloon inflation. This article will discuss how preconditioning migh...

Using a case example, we offer guidance for improving "difficult" clinician-patient relationships. These relationships may be repaired by acknowledging a clinician's part in conflict, empathizing with patients, identifying a patient's skill deficits, and employing communication and engagement techniques used by mental health professionals. Clinicians will inevitably take on more of the work of ...