OBJECTIVE Evaluate contamination on the external surfaces of cyclophosphamide vials available on the Canadian market during storage in pharmacy departments and the efficacy of decontaminating the external surfaces of vials using various cleaning techniques. METHODS The study consisted of three phases: the quantification of cyclophosphamide on the external surfaces of 10 vials of Procytox and ...

The efficacy of preventive and organisational measures implemented in Italy to prevent the contamination of cytotoxic drug preparation rooms has been investigated, and oncologic wards of two Italian hospitals were examined. The sampling strategy was based not only on potential sources of contamination but also on responses to detailed questionnaires on workplace practices and work organisation....

Selecting suitable cleaning agents and determining justifiable cleaning process parameters are critical prerequisites for cleaning validation. Proper selection of these cleaning agents and parameters could simplify cleaning validation efforts immensely. Process cleaners may range from a single component, such as an organic solvent, to multicomponent formulations that use multiple cleaning mecha...

INTRODUCTION It is not clear whether increasing the ultrasonic intensity would enhance the cleaning efficacy of passive ultrasonic irrigation (PUI) inside a root canal. The aim of this study was to evaluate the effect of the ultrasonic intensity on PUI to remove dentin debris and whether there is any lateral effect beyond the ultrasonic tip. METHODS Each of 15 in vitro root canal models with ...

Background. Efficient canal preparation is the key to successful root canal treatment. This study aimed to assess the cleaning and shaping ability, preparation time and file deformation of rotary, reciprocating and manual instrumentation in canal preparation of primary molars. Methods. The mesiobuccal canals of 64 extracted primary mandibular second molars were injected with India ink. The samp...

The waste associated with cleaning of process equipment is probably a significant contr ibutor to the total waste volume generated by industry. This paper addresses the following aspects related to equipment cleaning waste generation: o Review of reasons for cleaning process equipment o Reduction of cleaning frequency o Reduction of quantity and toxicity of cleaning waste o Costs associated wit...