in inferior leads (Fig. 1A). Cardiac enzymes showed an upward trend consistent with myocardial necrosis. Creatine kinase myocardial b (CKMB) fraction rose from 41.4 ug/L to 111.0 ug/L over 15 hours, while troponin I rose from undetectable levels on admission to >80.000 ug/L over the same period. He was treated as a non-ST elevation myocardial infarction with a thrombolysis in myocardial infarct...

INTRODUCTION Accidental hypothermia is a condition associated with significant morbidity and mortality. Hypothermia has been reported to affect left ventricular systolic and diastolic function. However, most of the data come from animal experimental studies. AIM OF THE STUDY The purpose of the present study was to assess the impact of severe accidental hypothermia on systolic and diastolic ve...

This study was carried out to evaluate the potential impact of nano hydroxyapatite (nano-HAp) intravenous injection with different concentrations on survival rates and the reaction affecting heart, liver and thyroid functions as well as the level of circulating nitric oxide. An inorganic-organic complexion route was selected for the synthesis of nano-HAp which was characterized by fourier trans...

Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction (AMI) patients immediately after admission and 24 hours after administration of thrombolytic agent streptokinase, and in healthy controls. Metho...

BACKGROUND In-stent restenosis is considered to be a gradual and progressive condition and there is scant data on myocardial infarction (MI) as a clinical presentation. METHODS AND RESULTS Of 2,462 consecutive patients who underwent percutaneous coronary intervention between June 2001 and December 2002, clinical in-stent restenosis occurred in 212 (8.6%), who were classified into 3 groups: ST...

OBJECTIVE We used a new graphical ordinal logit method (GOLDminer) to assess a single cardiac troponin T (cTnT) analysis at the time of admission (first generation monoclonal; Roche BMC Corp., Indianapolis, Indiana), the character of chest pain, and electrocardiographic (ECG)findings in predicting the likelihood of acute myocardial infarction (AMI) in patients presenting with suspected myocardi...

A 41-year-old commercial painter with a history of tobacco use presented to the emergency department with complaints of cough, pleuritic chest pain and worsening dyspnea with exertion beginning 3 days prior to arrival. He had not responded to an outpatient regimen of bronchodilators and antibiotics. The patient denied any constitutional symptoms. On initial examination, the patient was afebrile...

Creatine kinase (CK) isoenzymes MM, MB, and BB are located primarily in the cell cytosol, and increased CKMB in plasma is the hallmark of myocardial infarction. However, whether CK is released with reversible ischemic injury remains controversial. Here, we assessed plasma CK activity--cytosolic and mitochondrial CK--in serial samples (every 10 min for 60 min, then hourly or every 4 h for 48 h) ...

The study was to evaluate the roles of Adiponectin (ADP) in alleviating myocardial ischemia-reperfusion injury in rats with Remote Ischemic Postconditioning (RIP). A total of 57 healthy male SD rats were randomly divided into 3 groups (the sham operation group (S), the myocardial ischemia-reperfusion group (I/R), and the RIP group (R). The myocardial ischemia-reperfusion injury model was establ...