BACKGROUND We investigated whether circulating tumor cells (CTCs) and circulating endothelial cells (CECs) predict clinical outcome of first-line chemotherapy combined with bevacizumab in metastatic breast cancer patients. PATIENTS AND METHODS In a French substudy of the MO19391 trial, CTC and CEC counts (CellSearch system) at baseline and changes after two cycles of treatment were correlated...

Extracellular Vesicles and Circulating Nucleic Acids is an open access journal, focusing on extracellular vesicles circulating nucleic acids including DNA, RNA, miRNA their therapeutic use.

We study the interpixel cross talk introduced to digital holographic data storage by use of a multilevel phase mask at the data-input plane. We evaluate numerically the intensity distribution at the output detector for Fourier plane hologram storage in a limited-aperture storage medium. Only the effect at an output pixel of interpixel cross talk from the four horizontal and vertical neighboring...

To study the spiral wave in an unbounded excitable medium, we consider the wave front interaction model which derived by Zykov in 2007. This model consists of two systems of ordinary di↵erential equations which describe the wave front and wave back, respectively. First, we derive some properties of the back by shooting argument and comparison principle. Next we show the global existence of the ...

An overview is given of the attempts to understand the behavior of scroll waves in threedimensional excitable media using analytical methods, and these results are compared with recent numerical and experimental results. The behavior of untwisted planar scroll rings, twisted rings and helices, and knotted scroll wave filaments is discussed.

This work studies both theoretically and experimentally the formation of the contour interference patterns generated by a two-wavelength real-time holographic interferometer. The resulting contour interference fringes are due to the intersection of the measured surface with parallel, equally spaced planes of constant elevation. The theoretical analysis describes how the spatial frequency of the...

The understanding of metal nucleation on graphene is essential for promising future applications, especially of magnetic metals which can be used in spintronics or computer storage media. A common method to study the grown morphology is to measure the nucleated island density n as a function of growth parameters. Surprisingly, the growth of Fe on graphene is found to be unusual because it does ...