Apolipoprotein (apo)CIII predicts risk for coronary heart disease. We recently reported that apoCIII directly activates human monocytes. Recent evidence indicates that toll-like receptor (TLR)2 can contribute to atherogenesis through transduction of inflammatory signals. Here, we tested the hypothesis that apoCIII activates human monocytoid THP-1 cells through TLR2. ApoCIII induced the associat...

We obtained spectra of ASASSN-V J205543.90+240033.5 (J2055), a system that shows photometric variations similar to the white dwarf (WD) pulsar AR Scorpii (Kato et al. arXiv:2109.03979). Our display continuum rising steeply toward blue as well an array emission lines. Resolved Balmer and Paschen lines are seen with H$\alpha$ H$\beta$ having central absorption features. The strongest unresolved C...

Comparison of genomic DNA sequences from human and mouse revealed a new apolipoprotein (APO) gene (APOAV) located proximal to the well-characterized APOAI/CIII/AIV gene cluster on human 11q23. Mice expressing a human APOAV transgene showed a decrease in plasma triglyceride concentrations to one-third of those in control mice; conversely, knockout mice lacking Apoav had four times as much plasma...

We found that infection of Escherichia cell by lambda results in at least a twofold stimulation in the rate of synthesis of one of the products of groE. To determine what lambda-coded factors were responsible for this stimulation, numerous phage lambda mutants carrying bio substitutions were analyzed for their ability to stimulate groE synthesis. Our results revealed that the main factor(s) whi...

on expression of the Xrex+ gene, since little inhibition was observed following infection by a Xrex mutant or by a hybrid bacteriophage Xii44 which lacks a functional rex gene. For promotion of the synthesis of rex product, cII+ and N+ genes are required and can act trans, whereas cY+, also required, must be cis to a rex+ gene. These genes presumably play a role in the transcription of the cd-r...