introduction: the purpose of this in vitro study was to investigate the influence of 5.25% sodium hypochlorite (naocl) and 0.12% chlorhexidine gluconate (chx) use separately and combined as endodontic irrigants on the apical sealing ability of two endodontic sealers. materials and methods: eighty-six extracted maxillary central incisor teeth were used. the teeth were decoronated at the cej, acc...

OBJECTIVE The objective of this study was to examine the effects of sodium hypochlorite (NaOCl) and chlorhexidine (CHx) on cultured human periodontal ligament (PDL) cells in vitro. STUDY DESIGN The effects of irrigation solutions on human PDL cells were evaluated by propidium iodide fluorescence cytotoxicity assay, protein synthesis assay, and mitochondrial activity. RESULTS Both NaOCl and ...

Ventilator-associated pneumonia (VAP) is a common cause of morbidity, antibiotic use, increased length of stay and, possibly, increased mortality in ICU patients. Colonization of the oropharyngeal cavity with potentially pathogenic micro-organisms is instrumental in the pathogenesis of VAP, and selective oropharyngeal decontamination (SOD) with antibiotics (AB-SOD) or antiseptics, such as chlor...

OBJECTIVES The aim of this study was to compare the effects of four different mouthrinse containing propolis solutions and mouthrinse containing 0.2% chlorhexidine (CHX) on oral microorganisms and human gingival fibroblasts. METHODS Four different solutions of propolis were prepared and propylene glycol and alcohol were used as solvents for each propolis sample. Mouthrinse containing propolis...

Reactions between Mo(NAr)(CHR)(Me2Pyr)-(OTPP) (Ar = 2,6-i-Pr2C6H3, R = H or CHCMe2Ph, Me2Pyr = 2,5-dimethylpyrrolide, OTPP = O-2,3,5,6-Ph4C6H) and CH2=CHX where X = B(pin), SiMe3, N-carbazolyl, N-pyrrolidinonyl, PPh2, OPr, or SPh lead to Mo(NAr)(CHX)-(Me2Pyr)(OTPP) complexes in good yield. All have been characterized through X-ray studies (as an acetonitrile adduct in the case of X = PPh2). The...

STATEMENT OF THE PROBLEM Fixed orthodontic appliances predispose patients to dental caries. Use of mouthrinses has been introduced as the effective way for reducing dental plaque accumulation. PURPOSE The aim of this study was to compare the effects of Persica mouthwash and Chlorhexidine (CHX) on colonization of Streptococcus mutans (S. mutans) on fixed orthodontic O-rings. MATERIALS AND ME...

This study was evaluated the response of subcutaneous connective tissue of isogenic mice to calcium hydroxide-based pastes with chlorhexidine digluconate (CHX). Seventy isogenic male BALB/c mice aged 6-8 weeks and weighing 15-20 g were randomly assigned to 8 groups. The animals received polyethylene tube implants as follows: Groups I, II, and III (n=10) - Calen paste mixed with 0.4% CHX (experi...

AIM To evaluate the antibacterial activity of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) alone or associated with cetrimide (CTR), and QMiX against biofilm and planktonic Enterococcus faecalis (E. faecalis) [American type culture collection (ATCC) 29212]. MATERIALS AND METHODS The solutions 2.5% NaOCl, 2.5% NaOCl + 0.2% CTR, 2% CHX, 2% CHX + 0.2% CTR, 0.2% CTR, and QMiX were evaluate...

Root canal irrigants play a significant role in elimination of the microorganisms, tissue remnants, and removal of the debris and smear layer. No single solution is able to fulfill all these actions completely; therefore, a combination of irrigants may be required. The aim of this investigation was to review the agonistic and antagonistic interactions between chlorhexidine (CHX) and other irrig...

Introduction: Endocyn, a super-oxidized water-based irrigation solution, has been reported to be non-toxic against mammalian cells, yet highly efficacious against bacteria; however, its effect against fungi and fungal biofilms remain unknown. This study evaluated the antifungal efficacy of Endocyn compared to sodium hypochlorite (NaOCl) and chlorhexidine (CHX). Methods: An in vitro biofilm syst...