Chronic prurigo may reveal several internal diseases. Its association with a solid neoplasia is rare. We report an exceptional case of chronic prurigo revealing surgically curable adenocarcinoma of the ampulla of Vater. Our study involved a 70-year old patient, with no particular previous history, who was hospitalized for etiological assessment of prurigo lasting for 06 months associated with n...

To cite: Cowart D, Cowart KA, Hougeir FG. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-201434 DESCRIPTION A 39-year-old African-American woman presented with a 12-year history of ‘itchy dark spots all over my body,’ excluding the face and acral surfaces. The lesions are slightly pruritic at baseline. Flares occur frequently, however, mostly with friction ...

Arsenic is one of the most important toxicants in the environment. In Inner Mongolia of China, 300,000 residents are believed to be drinking water containing >50 microg/liter. Skin lesions have been known as the most common consequences resulting from chronic exposure to arsenic. To clarify the prevalence of arsenic-induced skin lesions, it is important to assess the impact of this problem amon...

Sir, Sarcoidosis is a chronic multi-system disease of unknown origin involving the eyes, skin, lungs, heart, bones and nerves. Skin lesions are relatively common, and are classified as either specific or non-specific (1). Specific lesions are those that show the typical sarcoid granulomas, including lupus pernio, infiltrated plaques, maculopapular eruptions, subcutaneous nodules and infiltratio...

Abstract Pemphigus Vulgaris is a chronic autoimmune mucocutaneous disease, in which oral lesions could be the first site observed, although skin and other mucous membranes may also be affected. Clinically, the lesions are characterized by many painful blisters that rapidly rupture resulting in erosions and/or multiple ulcers in the oral mucosa and skin, which can be difficult to differentiate f...

Sneddon's syndrome is characterized by chronic, progressive arteriopathy that causes ischemic stroke and skin lesions. It seems that thrombotic or embolic process in vessels may have role in its pathology. Neurological symptoms are always due to ischemic event of cerebrovascular system and skin manifestations include deep blue skin lesions with irregular margins called livedo reticularis and li...

Chronic radiodermatitis is defined as a chronic inflammation of the skin associated with exposure to ionizing radiation. It usually presents in individuals who, because of their profession, have been repeatedly exposed to low doses of radiation over a long period of time without appropriate protection. Several treatments have been described, including topical 5-fluorouracil, dermabrasion, ablat...

A 26-year-old male patient presented to our rheumatology clinic with pain, swelling and limitation of movement in his right ankle, and also purpuric skin lesions in the lower extremity pretibial region. He was asked questions, and he said that he had been having chronic low back pain and morning stiffness for the last few years. His physical examination revealed that he had arthritis in his rig...

Seven young men developed similar manifestations of disseminated candidiasis after a single episode of intravenous heroin abuse. Sequential development of lesions of the eye, skin, and bone or costal cartilage was noted within 10 days after injection. Skin lesions were confined to the scalp and other hair bearing areas. Candida albicans was cultured readily from affected skin and costal cartila...

Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of plasmacytoid dendritic cells (pDC) into the skin. The molecules involved in pDC accumulation in psoriasis lesions are unknown. Chemerin is the only inflammatory chemotactic factor that is directly active on human blood pDC in vitro. The aim of this study was to evaluate the role of the chemerin/C...