نتایج جستجو برای: chronic myeloid leukemia stem cells
تعداد نتایج: 2040664 فیلتر نتایج به سال:
introduction: leukemia is a malignant disorder resulting from clonal proliferation of lymphoid or myeloid precursors with arrested maturation. it has been shown recently that telomers and telomerase activity are involved in the control of cell proliferation, regulation of cell senescence in the most somatic cells, and unlimited proliferation capacity of the malignant cells including leukemic ce...
INTRODUCTION Chronic myeloid leukemia is the first malignant disease to be associated with a genetic lesion and is the first leukemia to provide a genotype model conducive to targeted molecular therapy. It is a chronic clonal myeloproliferative disorder, originating in a pluripotent stem cell common to all three hematopoietic lineages, characterized by overproduction of myeloid cells in all sta...
Chronic myeloid leukemia (CML) is commonest type of chronic leukemia in India. It has achieved enormous attention in the medical literature because of the delineation of its molecular basis and the discovery of successful targeted therapy in the form of tyrosine kinase inhibitor, imatinib. Chronic myeloid leukemia is defined as a myeloproliferative disease that originates in an abnormal pleurip...
Metaphase-fluorescence in situ hybridization analyses, based on as many as 1000 cells were performed on 361 bone marrow specimens to monitor the level of residual disease after allogeneic stem cell transplantation in 102 patients with chronic myeloid leukemia. Residual cells were detected in 33 patients. No spontaneous eradication of residual cells was observed when the frequency of the cells e...
Introduction Lymphoma is a hematologic malignancy characterized by nodal or extranodal malignant infiltration by monoclonal lymphoid cells (B lineage cells in 70% of the cases). Its etiology is not precisely known. Prolonged life expectancy has resulted in increase of the disease incidence. Marginal zone lymphoma is a low-grade small B-cell lymphoma incorporated in the World Health Organization...
24Boyse, E. A., L. J. Old, G. Geering, and E. Stockert, unpublished observations. 25 Cells from 4 cases of human leukemia (acute leukemia in a child, acute myeloid leukemia, chronic myeloid leukemia, and chronic lymphatic leukemia) were obtained through the courtesy of Dr. B. Clarkson, Dr. L. Murphy, and Dr. C. Tan of Sloan-Kettering Institute. These cells did not acquire sensitivity to Rausche...
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we have two part in this thesis, at first: the interaction of native calf thymus dna (ct-dna) with two anthraquinones including quinizarin (1,4- dihydroxy anthraquinone) and danthron (1,8- dihydroxy anthraquinone) in a mixture of 0.04 m brittone-robinson buffer and 50% of ethanol were studied at physiological ph by uv-vis absorption, florescence, circular dichroism spectroscopic methods, viscos...
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