recombinant human interferon alpha 2a (rhifn α -2a) production and cell growth were monitored in a set of genetically modified e. coli strains (msd1519, msd1520, msd 1521, msd 1522, msd 1523) producing rhifn α -2a. the growth was followed at od 600 nm, changes in cell physiology were detected by pyrolysis mass spectrometry (pyms) of cell biomass and recombinant protein production was determined...

Chronic exposure of cells to expanded polyglutamine proteins results in eventual cell demise. We constructed mouse cell lines expressing either the full-length androgen receptor (AR), or truncated forms of AR containing 25 or 65 glutamines to study the cellular consequences of chronic low-level exposure to these proteins. Expression of the polyglutamine-expanded truncated AR protein, but not th...

this study was carried out to investigate the possibility of prediction the occurrence of heat stress in dairy cows and determination of climate critical periods. the most common indexes for estimation the degree of thermal stress istemperature humidity index (thi). in this study yousef’s thi index (1985)was used to analyze the yearly and monthly effects of temperature and humidity. meteorologi...

the main aim is to study the two dimensional axisymmetric problem of thick circular plate in modified couple stress theory with heat and mass diffusive sources. the thermoelastic theories with mass diffusion developed by sherief et al. [1] and kumar and kansal [2] have been used to investigate the problem. laplace and hankel transforms technique is applied to obtain the solutions of the governi...

this study was conducted to investigate the effects of different levels of zinc sulfate and chromium picolinate on performance, body temperature, carcass characteristics, tibia ash and serum biochemical parameters of japanese quails under heat stress condition. the birds (n = 540; 7-d-old) were randomly assigned to 9 treatment groups consisting of 3 replicates of 20 birds each in a 3 × 3 factor...

Chronic exposure to environmental heat improves tolerance via heat acclimation (AC). Our previous data on mammals indicate that reprogramming the expression of genes coding for stress proteins and energy-metabolism enzymes plays a major role. Knowledge of pathways leading to AC is limited. For their identification, we established a Caenorhabditis elegans AC model and tested mutants in which sig...

Within their natural habitat, plants are subjected to a combination of abiotic conditions that include stresses such as drought and heat. Drought and heat stress have been extensively studied; however, little is known about how their combination impacts plants. The response of Arabidopsis plants to a combination of drought and heat stress was found to be distinct from that of plants subjected t...

Introduction: Stress is a main factor influencing brain functions as revealed by the electroencephalogram (EEG) recordings. Moreover, different stress durations seemingly cause perturbations in brain waves and lead to mental disorders. This study investigates the effects of acute, sub-chronic and chronic stress on EEG in rats.  Methods: Twenty-eight Wistar adult male rats were randomly all...

BACKGROUND Increased oxidative stress may play a role in morbidity and mortality of patients with renal failure. Most studies have examined serum markers of oxidation, but it is unclear whether oxidative stress is involved in skeletal muscle atrophy. METHODS This study examined markers of oxidative stress in the skeletal muscle of 10 haemodialysed patients and 10 control subjects. Biopsies fr...