نتایج جستجو برای: cholesterol ester transfer protein

تعداد نتایج: 1585710  

2018
Joelle Ayoub

Background: Many studies have shown that a reduction in low-density lipoprotein cholesterol (LDL-C) is associated with lower risk of cardiovascular disease. It has been suggested that the reduction of cardiovascular risk is proportional to the reduction in LDL-C. However, cholesteryl ester transfer protein (CETP) inhibitors have not been shown to follow this pattern. These medications increase ...

2018

Submitted by arnett on Mon, 08/19/2013 3:11pm Title The effect of a novel intergenic polymorphism (rs11774572) on HDL-cholesterol concentrations depends on TaqIB polymorphism in the cholesterol ester transfer protein gene. Publication Type Journal Article Year of Publication 2010 Authors Junyent, M, Lee, Y-C, Smith, CE, Arnett, DK, Tsai, MY, Kabagambe, EK, Straka, RJ, Province, M, An, P , Lai, ...

Journal: :Current opinion in lipidology 2008
Richard A Krasuski

The year 2011 has thus far been dominated by the vigorous pursuit of interventions for patients with low levels of high-density lipoprotein cholesterol (HDL-C) and proatherogenic lipid profiles. The major setback of the early stoppage of the Atherothrombosis Intervention in Metabolic Syndrome with Low HDL Cholesterol/ High Triglyceride and Impact on Global Health Outcomes (AIM-HIGH) trial by th...

2017

published by arnett on Mon, 08/19/2013 3:11pm Title The effect of a novel intergenic polymorphism (rs11774572) on HDL-cholesterol concentrations depends on TaqIB polymorphism in the cholesterol ester transfer protein gene. Publication Type Journal Article Year of Publication 2010 Authors Junyent, M, Lee, Y-C, Smith, CE, Arnett, DK, Tsai, MY, Kabagambe, EK, Straka, RJ, Province, M, An, P , Lai, ...

Journal: :Arteriosclerosis 1990
M Abbey P Clifton M Kestin B Belling P Nestel

A group of 33 mildly hypercholesterolemic men were stratified into three groups on diets closely matched except for the polyunsaturated fatty acid supplement. The first group received 14 g/day of linoleic acid (safflower oil); the second group, 9 g of alpha-linolenic acid (linseed oil); and the third group, 3.8 g of n-3 fatty acids (fish oil). Only fish oil lowered plasma triglycerides (by 24% ...

Objective: Cholesteryl Ester Transfer Protein (CETP) mediates the transfer of cholesteryl ester from HDL-C to LDL-C and VLDL-C. The aim of the present trial was to evaluate the effect of curcumin and its modified formulation on serum CETP concentrations in patients with metabolic syndrome. Materials and Methods: Participants were randomly allocated to one of three groups of 40 subjects receivin...

Objective(s): This study aims to investigate joint association between cholesterol ester transfer protein (CETP) polymorphisms and body mass index (BMI) or birth weight with the risk of dyslipidemia in Iranian children and adolescents. Materials and Methods:This study was conducted as a sub-study of the “school-based nationwide health survey” (CASPIAN-III). We randomly selected 750 samples from...

2009
Eder de Carvalho Pincinato Patricia Moriel Dulcinéia Saes Parra Abdalla

Cholesterol oxides are atherogenic and can affect the activity of diverse important enzymes for the lipidic metabolism. The effect of 7b-hydroxycholesterol, 7-ketocholesterol, 25-hydroxycholesterol, cholestan-3b,5a,6b-triol,5,6b-epoxycholesterol, 5,6a-epoxycholesterol and 7a-hydroxycholesterol on esterification of cholesterol by lecithin:cholesterol acyl transferase (LCAT, EC 2.3.1.43) and the ...

Journal: :Cardiovascular research 2008
Urbain Tchoua Wilissa D'Souza Nigora Mukhamedova Denise Blum Eric Niesor Jacques Mizrahi Cyrille Maugeais Dmitri Sviridov

AIMS Cholesteryl ester transfer protein (CETP) has a well-established role in lipoprotein metabolism, but the effect of its overexpression or inhibition on the efficiency of reverse cholesterol transport (RCT) is unclear. METHODS AND RESULTS Neither overexpression of CETP nor treatment with CETP inhibitor Torcetrapib of RAW 264.7 macrophages or HepG2 hepatocytes affected cholesterol efflux in...

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