the objective was to investigate the presence of mycoplasma and chlamydia in the synovial fluid of patients with rheumatoid arthritis (ra) and other chronic arthritides. samples of synovial fluid (sf) were collected from all patients presenting with an articular effusion. seventy sf samples were subjected to study for mycoplasma and cultured on standard media for mycoplasma. the 70 other sf sam...

UNLABELLED Chlamydia trachomatis is an important bacterial pathogen known to be etiological in genital infections, as well as several serious disease sequelae, including inflammatory arthritis. Chlamydiae can persist in infection, making treatment with antibiotics such as azithromycin (AZ) a challenge. The authors explore the use of neutral generation-4 polyamidoamine (PAMAM) dendrimers as intr...

There are no examples of stable tetracycline resistance in clinical strains of Chlamydia trachomatis. However, the swine pathogen Chlamydia suis is commonly tetracycline resistant, both in America and in Europe. In tested U.S. strains, this resistance is mediated by a genomic island carrying a tet(C) allele. In the present study, the ability of C. suis to mobilize tet(C) into other chlamydial s...

background: chlamydia trachomatis (ct) is a common cause of sexually transmitted infections (sti) and a prevalent microorganism found in the vaginal discharge of sexually active women. the infection usually has no symptoms; although it may cause chronic complications such as pelvic inflammatory disease (pid), ectopic pregnancy, chronic pelvic pain, tubal infertility and cervical cancer. this st...

females abortion is one of the most important sequela of genital infection with chlamydia trachomatis, mycoplasma hominis and ureaplasma urealyticum.in this study frequency of chlamydia trachomatis, mycoplasma hominis and ureaplasma urealyticum was studied in 125 females with habitual abortion by direct and indirect immunofluorescence tests and culture method and compared with 250 normal popula...

Chlamydia trachomatis is an obligate intracellular bacterium that infects the oculogenital mucosae. C. trachomatis infection of the eye causes trachoma, the leading cause of preventable blindness. Infections of the genital mucosae are a leading cause of sexually transmitted diseases. A vaccine to prevent chlamydial infection is needed but has proven difficult to produce by using conventional va...

Solid-phase-based immunoassays have traditionally been plagued by nonspecific binding to the solid phase and by slow reaction kinetics relative to reactants that are free to diffuse in solution. We have developed two novel immunoassays in which the solid phase is generated in situ after the specific binding reaction has occurred, thereby enhancing reaction kinetics and minimizing the opportunit...