The high performance liquid chromatography (HPLC) enantioseparation of four β-blocking agents metoprolol, bisoprolol, propranolol and atenolol was performed on amylose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase using n-hexane-ethanol-diethylamine (DEA) as the mobile phase and related chiral recognition mechanisms were discussed. Enantiomeric separation of the fourβ-blockers was ...

Modafinil [2-[(diphenylmethyl)sulfinyl]acetamide] is used clinically in the treatment of narcolepsy and sleeping disorders. The synthesis of modafinil, begins with the reaction of benzhydrol and thioglycolic acid in trifluoroacetic acid to afford benzhydrylsulfinyl acetic acid. The reaction of acid with thionyl chloride in benzene followed by treatment with ammonium hydroxide gave acetamide...

Conventional mirrors convert right-handed circularly polarized waves (RCP) into left-handed circularly polarized waves (LCP) and vice versa, see Fig. 1(a-c). Here we demonstrate a novel type of chiral mirror that will reflect one circular polarization without changing its handedness, while absorbing waves of the opposite handedness, see Fig. 1(d-f). This functionality, which fundamentally relie...

The concentration of a chiral solution is key parameter in many scientific fields and industrial processes. This can be estimated to high precision by exploiting circular birefringence or dichroism present optically active media. Using the quantum Fisher information formalism, we quantify performance Gaussian probes estimating analytes. We find that bright-polarization squeezed state provide ad...

A bstract We employ path integral methods to calculate the Casimir energy and force densities in a chiral extension of QED. Manifestly gauge invariant perfect electromagnetic boundary conditions, natural generalization electric magnetic are implemented directly action by usage auxiliary fields. The properties vacuum modelled using background θ field, we introduce techniques efficiently this med...