Essential oil of Juniperus oxycedrus growing in Algeria was obtained by steam distillation extraction method. The oil was analysed by capillary columns (non-polar DB5 and HP-chiral-20B) using gas chromatography with flame ionization and mass spectrometric detections. The compounds were identified according to their retention indices and mass spectra (EI, 70 eV). The oil contained α-pinene (36.7...

Recently, it has been found that room-temperature ionic liquids can be used as stable, unusual selectivity stationary phases. They show "dual nature" properties, in that they separate nonpolar compounds as if they are nonpolar stationary phases and separate polar compounds as if they are polar stationary phases. Extending ionic liquids to the realm of chiral separations can be done in two ways:...

Phenylcarbamate derivatives of amylose and β-cyclodextrin show excellent chiral recognition when used as chiral stationary phases (CSPs) for high-performance liquid chromatography. To open up new possibilities of carbohydrate-based materials, we developed chiral fluorescent sensors based on amylose and β-cyclodextrin (Am-1b and CyD-1b, respectively) by attaching fluorescent π-conjugated units o...

A common approach in resolving enantiomers of chiral basic drugs by capillary electrophoresis (CE) is to use cyclodextrins (especially their anionic derivatives) as chiral selector in the acidic buffer (pH ≤ 3) in normal or reversed (carrier) mode. Then, some organic modifiers are added to the buffer solution if the resolution is not satisfactory. In case of cetirizine (CTN), applying the same ...

A set of 42 chiral compounds containing stereogenic sulfur was prepared. There were 31 chiral sulfoxide compounds, three tosylated sulfilimines and eight sulfinate esters. The separations were done using five different macrocyclic glycopeptide chiral stationary phases (CSPs), namely ristocetin A, teicoplanin, teicoplanin aglycone (TAG), vancomycin and vancomycin aglycone (VAG) and seven eluents...

The current developments in liquid chromatography-mass spectrometry (LC-MS) and its applications to the analysis of pharmaceuticals are reviewed. Various mass spectrometric techniques, including electrospray and nanospray ionization, atmospheric pressure chemical ionization and photoionization and their interface with liquid chromatographic techniques are described. These include high performan...

phase together with a counterion. Schurig V (1984) Gas chromatographic separation of enantiomers on optically active stationary phases. Angewarde Chemie International Edition English 23: 747}765. Schurig V (1994) Enantiomer separation by gas chromatography on chiral stationary phases. Journal of Chromatography 666: 111}129. Schurig V and Nowotny H-P (1990) Gas chromatographic separation of enan...

Molecularly imprinting polymers (MIPs) have been extensively applied in chromatography for the separation of chiral drugs. In this review, we mainly summarize recent developments of various MIPs used as chiral stationary phases (CSPs) in high performance liquid chromatography (HPLC), capillary electrochromatography (CEC), and supercritical fluid chromatography (SFC). Among them, HPLC has the ad...