Patients with childhood, adolescent, and young adult cancer who will be treated gonadotoxic therapies are at increased risk for infertility. Many patients their families desire biological children but effective communication about treatment-related infertility procedures fertility preservation does not always happen. The PanCareLIFE Consortium the International Late Effects of Childhood Cancer ...

OBJECTIVE The aim of this study was to characterise rates of late mortality and second cancers in an Australian cohort of childhood cancer survivors and compare these to rates observed in the New South Wales population. DESIGN, SETTING AND PARTICIPANTS Records for 896 childhood cancer survivors treated at the Sydney Children's Hospital between 1972 and 1999 were linked to the National Death I...

PURPOSE To estimate the number of individuals in the United States diagnosed with cancer as children (ages 0-19 years) as of 2005, with a focus on those surviving for >30 years. METHODS To estimate the national prevalence of survivors of childhood cancers, we used data from the Surveillance Epidemiology and End Results program from 1975 to 2004. Long-term childhood cancer survivors, diagnosed...

Childhood cancers are a broad range of diseases. Research on the chemopreventive potential of non-steroidal anti-inflammatory drugs, such as aspirin (acetylsalicylate) has yet to be fully directed towards childhood cancers. A prima facie hypothesis on salicylate and childhood cancer would therefore be based on several factors. Firstly, salicylate inhibits the production of inflammatory prostagl...

The carcinogenic effects of exposure to ionizing radiation vary markedly with age, as revealed by studies of Japanese atomic bomb survivors and of Marshall Islanders exposed to fallout from U.S. nuclear weapons tests in the South Pacific in 1954. An increase in cancers of adulthood after intrauterine exposure, as reported in 1988, has not been sustained. After childhood exposure, increases in l...

OBJECTIVE This paper presents the incidence rates of childhood cancers using the data obtained from Golestan population based cancer registry (GPCR) between 2004 and 2006. METHODS GPCR registers only primary cancers based on standard protocols of the international association of cancer registries (IACR). We collect data on newly diagnosed (incident) cancer cases from all public and private di...

OBJECTIVE To examine childhood cancer risks associated with exposure to diagnostic radiation and ultrasound scans in utero and in early infancy (age 0-100 days). DESIGN Case-control study. SETTING England and Wales. PARTICIPANTS 2690 childhood cancer cases and 4858 age, sex, and region matched controls from the United Kingdom Childhood Cancer Study (UKCCS), born 1976-96. MAIN OUTCOME ME...

Childhood cancer survivorship is a national public health priority, with an increasing number of survivors who face late effects from both disease and treatment. As childhood cancer survivors are living into adulthood, care of the late effects associated with their diagnosis and treatment can become complex. Often these patients no longer have follow-up with the treating pediatric hospital and ...

The goal of this case report is to describe the young childhood cancer survivor who was treated for non‑Hodgkin lymphoma with chemotherapy containing anthracycline doxorubicin and developed symptoms serious cardiovascular damage 27 years after diagnosis cancer. patient in long‑term complete remission lymphoma. He started guideline medical therapies chronic heart failure had a cardio...