There has been a dramatic increase in the number of childhood cancer survivors living to an old age due to improved cancer treatments. However, these survivors are at risk of numerous late effects as a result of their cancer therapy. Engaging in protective health behaviors and limiting health damaging behaviors are vitally important for these survivors given their increased risks. We reviewed t...

The causes of childhood cancer have been systematically studied for decades, but apart from high-dose radiation and prior chemotherapy there are few strong external risk factors. However, inherent risk factors including birth weight, parental age, and congenital anomalies are consistently associated with most types of pediatric cancer. Recently the contribution of common genetic variation to et...

Abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. We report an 11 years old girl who developed central hypothyroidism and ACTH deficiency during the chemotherapy for CNS relapse of acute lymphoblastic leukemia before receiving radiotherapy. Keywords: Thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leu...

In 2007, almost 10,400 American children younger than 15 years were diagnosed with cancer, with approximately 1,545 dying from the disease (National Cancer Institute, 2009). In Britain, the risk of a child younger than 15 years being diagnosed with cancer is about 1 in 500 (Cancer Research UK, 2009). Significant improvements have been made in five-year relative survival from childhood cancers, ...

My 12-year-old daughter recently visited Children’s Hospital on a school field trip for science class. Although the purpose of the visit was to peer into the microscopes in the hospital laboratory, my daughter and her classmates saw several children in the waiting areas and hallways. Many were presumably being treated for cancer, which prompted the class’s collective response of “it’s so sad, s...

background: childhood obesity is becoming a global problem and its incidence is increasing. the role of dietary intervention with fruits containing vitamin c and flavonoid to control obesity consequences in childhood has not been yet defined. lemon (citrus aurantifolia) peels contain flavonoid, pectin and vitamin c. we aimed to compare the effects of lemon peels and placebo on cardiometabolic r...

Background: To explore a possible rela!onship among blood groups and the prognosis of breast cancer, this case- control study was carried out in Arak city, Arak province, Iran. Materials and Methods: One hundred and thirty four pa!ents with breast cancer were inves!gated. ABO blood groups were obtained from medical records. Mul!variate analyses were performed, including size of tumor, axilla...

background while colorectal cancer (crc) is one of the most preventable causes of cancer mortality, it is one of the leading causes of cancer death in canada where crc screening uptake is suboptimal. given the increased rate of mortality and morbidity among mental health patients, their condition could be a potential barrier to crc screening due to greater difficulties in adhering to behaviours...

Uric acid has been proposed as an important risk factor in the development of primary hypertension in humans. However, limited information is available linking childhood uric acid levels and blood pressure levels in adulthood. This study examined 334 whites and 243 blacks enrolled in the Bogalusa Heart Study as children aged 5 to 17 years and as adults aged 18 to 35 years. The average follow-up...