BACKGROUND/AIMS Single optotype tests of visual acuity are widely used for preschool vision screening in order to optimise cooperation with testing. These tests may, however, underestimate the visual acuity deficit in amblyopia because they lack visual crowding. This study assessed the resultant negative predictive value (NPV) for amblyopia. METHODS Cohort study of 936 children in the Cambrid...

Aim: To offer a critique of current methods of defining amblyopia treatment outcome and to examine alternative approaches. Method: Literature appraisal and descriptive case presentations. Results: Currently, the outcome of amblyopia treatment is expressed as the number of acuity chart lines gained or, alternatively, achievement of an arbitrarily adopted level of visual acuity. As binocular visi...

There is growing evidence for deficits in motion perception in amblyopia, but these are rarely assessed clinically. In this prospective study we examined the effect of occlusion therapy on motion-defined form perception and multiple-object tracking. Participants included children (3-10years old) with unilateral anisometropic and/or strabismic amblyopia who were currently undergoing occlusion th...

PURPOSE Several behavioral studies have shown that the reaction times of visually guided movements are slower in people with amblyopia, particularly during amblyopic eye viewing. Here, we tested the hypothesis that the initiation of smooth pursuit eye movements, which are responsible for accurately keeping moving objects on the fovea, is delayed in people with anisometropic amblyopia. METHODS...

Citation: Xi J, Jia W-L, Feng L-X, Lu Z-L, Huang C-B. Perceptual learning improves stereoacuity in amblyopia. Invest Ophthalmol Vis Sci. 2014;55:2384–2391. DOI:10.1167/ iovs.13-12627 PURPOSE. Amblyopia is a developmental disorder that results in both monocular and binocular deficits. Although traditional treatment in clinical practice (i.e., refractive correction, or occlusion by patching and p...

AIMS To describe the effect of amblyopia on education, occupation, and 5 year incident vision loss. METHODS 3654 participants aged 49 years or older participated in the Blue Mountains Eye Study (BMES I, 1992-4) and 2335 (75.1% of survivors) were re-examined (BMES II, 1997-9). All participants underwent detailed eye examination. Amblyopia, defined as best corrected visual acuity of less than o...

The effects of unilateral lid closure and artificial esotropia on the development of visual acuity were studied in visually immature rhesus monkeys (Macaca mulatta). Irreversible amblyopia occurred in all animals whose lids were sutured between birth and nine weeks of age. Lid closure at the age of 12 weeks did not produce amblyopia. During the age of susceptibility only brief periods of occlus...

Disruption of visual input to one eye during early development leads to marked functional impairments of vision, commonly referred to as amblyopia. A major consequence of amblyopia is the inability to encode binocular disparity information leading to impaired depth perception or stereo acuity. If amblyopia is treated early in life (before 4 years of age), then recovery of normal stereoscopic fu...