نتایج جستجو برای: chemerin
تعداد نتایج: 677 فیلتر نتایج به سال:
PURPOSE The inflammatory state of adipose tissue in obese subjects may be the most important factor linking increased adipose tissue mass to insulin resistance. Chemerin is a newly discovered adipokine that plays an important role in macrophage infiltration into adipose tissue and may contribute to the development of inflammation and insulin resistance. We examined the effects of 12 weeks of ae...
Chemerin is an adipokine proposed to link obesity and chronic inflammation of adipose tissue. Genetic factors determining chemerin release from adipose tissue are yet unknown. We conducted a meta-analysis of genome-wide association studies (GWAS) for serum chemerin in three independent cohorts from Europe: Sorbs and KORA from Germany and PPP-Botnia from Finland (total N = 2,791). In addition, w...
OBJECTIVES Chemerin and interleukin (IL)-8 are pro-inflammatory mediators whose role in joint inflammation and cartilage degradation has been demonstrated in in-vitro findings. Studies on their presence in synovial fluid (SF) samples may offer further information on their pathogenic role. The aim of this study was to investigate SF chemerin and IL-8 levels in patients with different joint disea...
Inflammation appears to be the cause of aortic valve (AoV) stenosis and identification of predictive biomarkers is therefore imperative. The aim of the current study was to evaluate the potential role of serum chemerin and fibroblast growth factor-21 (FGF-21) in the pathogenesis of the disease. A total of 102 patients were selected based on certain criteria and divided into an aortic stenosis g...
Mesenchymal stem cells (MSCs) play important roles in tissue repair and cancer progression. Our recent work suggests that some mesenchymal cells, notably myofibroblasts exhibit regulated exocytosis resembling that seen in neuroendocrine cells. We now report that MSCs also exhibit regulated exocytosis. Both a G-protein coupled receptor agonist, chemerin, and a receptor tyrosine kinase stimulant,...
Background & Aims: Chemerin is one of the adipocines that is secreted in the form of prochemerin from visceral fat, liver, adipose tissue, aorta and coronary artery wall, and can be considered as a predictor of cardiovascular disease particularly in elderly men. This study was carried out to evaluate the effect of eight weeks of endurance and resistance training on chemerin level, insulin resis...
Background and Objective: Chemerin and vaspin are adipose tissue-driven adipokines and appear to be associated with inflammation and insulin resistance. The aim of this study was to investigate the effect of 12 weeks of aerobic interval training on chemerin, vaspin and insulin resistance index in overweight students. Materials and Methods: Twenty four male students voluntarily participated in t...
Inhalation of ozone (O3), a gaseous air pollutant, causes lung injury, lung inflammation, and airway hyperresponsiveness. Macrophages, mast cells, and neutrophils contribute to one or more of these sequelae induced by O3 Furthermore, each of these aforementioned cells express chemokine (C-C motif) receptor-like 2 (Ccrl2), an atypical chemokine receptor that facilitates leukocyte chemotaxis. Giv...
The purpose of our study was to observe adipokine expression and endothelial function in subclinical hypothyroidism (sHT) rats and to determine whether levothyroxine (LT4) treatment affects these changes. Sixty-five male Wistar rats were randomly divided into five groups: the control group; sHT A, B and C groups and the sHT + T4 group. The sHT rats were induced by methimazole (MMI) and the sHT ...
Objective: It was aimed to investigate irisin and chemerin levels in prediabetic individuals their value predicting prediabetes.
 Method: Thirty-eight patients aged 18-65 years (22 impaired fasting glucose (IFG), 10 tolerance (IGT), 6 with coexisting IFG IGT) thirty-five healthy volunteers were included which designed as a cross-sectional study. The basic demographic characteristics of all...
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