Air Chek, Inc. is performing survey of over 16,000 households that have tested for radon gas. Rather than attempt to conduct a complete epidemiologic study, the intention is to demonstrate a method of locating lung cancer victims within neighborhoods based on the likelihood that the majority of the structures will have radon measurement levels within a similar range. A preliminary survey was ma...

Background and aims CHEK2 gene is located on chromosome 22q12.1. and encodes the human analogue of the yeast checkpoint kinases Cds1 and Rad 53. Activation of CHEK2 in response to DNA damage prevents the cell from entering into mitosis. Three founder alleles are present in Poland. Two of these result in a truncated CHEK2 protein IVS2+1G>A in exon 3 and 1100 del C in exon 10, the other, I157T is...

OBJECTIVE To assess a new immunochromatography (ICT) test that detects glutamate dehydrogenase (GDH) antigen and Clostridium difficile toxin A/B simultaneously, and to propose an algorithm for the diagnosis of C. difficile infection (CDI) based on this test. METHODS We analysed 970 stool samples. Discrepant results between GDH and toxin A/B were resolved using toxigenic culture as the referen...