Increased nonspecific bronchial hyperresponsiveness to pharmacological agents such as histamine or methacholine (MCh) is a hallmark of asthma. The measurement of airway reactivity is quite sensitive but testing is tedious, and time and money consuming. The present aim was, therefore, to design the shortest possible, yet safe inhalation challenge protocol applicable for a lung function referral ...

This paper targets the growing area of interactive data analytics engines. We present a system called Getafix that intelligently decides replication levels and replica placement for data segments, in a way that is responsive to changing popularity of data access by incoming queries. We present an optimal solution to the static version of the problem, achieving minimality in both makespan and re...

Efficient nutrient usage is a trait under universal selection. A substantial part of cellular resources is spent on making nucleotides. We thus expect preferential use of cheaper nucleotides especially in transcribed sequences, which are often amplified thousand-fold compared with genomic sequences. To test this hypothesis, we derive a mutation-selection-drift equilibrium model for nucleotide s...

HVDC transmission is more effective and economically cheaper where bulk power is to be transmitted over long distance. Hence the surplus power from a remote place can be exported to the needy place at cheaper rate. The HVDC system require only one transmission wire and the ground return or seawater can be used as an another line. The Lakshadweep Island is located at faraway place from the north...