Recently, many emerging circular RNAs (circRNAs) have been studied in human malignancies including cervical cancer and are involved tumor development oncogenesis. Here, we found that circABCB10 was higher 58 tissue sample than the adjacent normal tissues. Higher expression significantly associated with advanced International Federation of Gynecology Obstetrics (FIGO) stage greater lymphatic inv...

Secreted protein acidic and rich in cysteine (SPARC) is associated with the progression of numerous types of cancer. However, the role of SPARC in the progression of cervical cancer has not yet been adequately elucidated. In the current study, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and immunohistochemistry were employed to evaluate the mRNA and protein expression...

Objective: To detect the expression of histone deacetylase 3 (HDAC3) in cervical cancer tissue and investigate the inhibition of HDAC3 by Small Interference RNA (siRNA) on the effect of HDAC3 in Hela cell line of cervical cancer. Methods: The expression of HDAC3 in 12 specimens of normal cervical tissues, 21 specimens of moderate to severe cervical intraepithelial neoplasia and 64 specimens of ...

We present the case of a 40 years old female presenting with a solitary apical lung mass, associated Horneŕ syndrome and evidence of medullary compression. Although she had a history of cervical cancer, a primary lung tumor was suspected. Tissue biopsy confirmed cervical cancer metastasis, highlighting the fact that although metastasis usually presents as multiple lung nodules, solitary lesions...

conclusions the results of this meta-analysis showed that gardasil and cervarix vaccines are highly effective against cervical cancer. according to the point that approximately 50% of cervical cancers and human carcinogenicity are related to hpv-16 infection, the bivalent hpv vaccine might have protective effects against hpv-16 cin2-3 lesion and cervical cancer. results by combining the results...

the rate of cervical cancer in asians is deferent, based on the risk factors affecting and the rate of papiloma virus infection among females. cervical cancer is one of the important cancers between iranian women. in the present study the rate of cervical neoplasia was detected in isfahan and some risk factors affecting the incidence of cervical cancer was analyzed. the human papiloma virus inf...

background: the accuracy of diagnostic assays in human papillomavirus (hpv) genital infection and cervical cancer has remained a clinical challenge in diagnosis.  evidence indicates that a large proportion of cervical cancer can be prevented through organized care for hpv and testing. countries with low per capita income, such as iran and its neighbours, have no national organized program for c...

BACKGROUND To investigate the implication of ribonucleotide reductase M2 (RRM2) in the carcinogenesis of uterine cervix and its relationship with clinicopathological characteristics and prognosis of cancer patients. METHODOLOGY AND PRINCIPAL FINDINGS The impact of RRM2 on cell viability was investigated in SiHa cervical cancer cells after RRM2 knockdown and the addition of cisplatin, which in...