Objective Cerebrospinal fluid (CSF), its secretion, circulation and absorption have been the subject of recent researches. There is a general agreement that the main site of CSF secretion is in the choroids plexus. However, the main absorption site is controversial. Some believe that arachnoid granulations are the principle sites of CSF absorption. In this study, different locations of CSF abs...

Cerebrospinal fluid (CSF) is the biological fluid in closest contact with the brain and thus contains proteins of neural cell origin. Hence, CSF is a biochemical window into the brain and is particularly attractive for the search for biomarkers of neurological diseases. However, as in the case of other biological fluids, one of the main analytical challenges in proteomic characterization of the...

Cerebrospinal fluid (CSF) analysis is one of the most important tests in diagnosis central nervous system (CNS) diseases. Although CSF commonly used neurological pathological conditions, it also has its place psychiatry. Studies to date have described several valuable specific cytomorphological phenomena cerebrospinal patients with acute schizophrenia, which indicate inflammatory or immune-medi...

Mutation of the granulocyte-macrophage colony-stimulating factor (GM-CSF) gene by homologous recombination caused alveolar proteinosis in mice. To further discern the role of GM-CSF in surfactant homeostasis, the synthesis of GM-CSF was directed to the respiratory epithelium of GM-CSF-hull mutant mice (GM-/-) with a chimeric gene expressing GM-CSF under the control of the promoter from the huma...

studying csf (cerebro spinal fluid) is a simple and fast measure for diagnosing meningitis in children. for this reason, lp [umbar puncture] is used to treat csf.  regarding the side effects of lp, we decided to determine the positive points observed in the patients’ files than total patients confined to bed in our selected population. in this study conducted by descriptive retrospective method...

despite recent innovations in the laboratory diagnosis of bacterial from nonbacterial meningitis, solid data-necessary for early determination of bacterial meningitis (bm) before organism growth in the culture medium-are missing. therefore cerebrospinal fluid (csf) lactate levels were evaluated as a possible means of differentiating the two clinical entities. this was a retrospective study. pat...

26 J Kor Neurotraumatol Soc Cerebrospinal fluid (CSF) rhinorrhea involves a breakdown of all barriers that separate the subarachnoid space from the upper aerodigestive tract, namely, the mucosa of the nasal cavity or paranasal sinus, skull base, dura mater, and arachnoid membrane. CSF rhinorrhea expressed as meningitis, subdural empyema or brain abscess, when inadequately treated 3,19) . CSF fi...

Cerebrospinal fluid (CSF) plays a vital role in the immunological support, structural protection and metabolic homeostasis of the central nervous system (CNS). CSF is a clear fluid that surrounds the entire brain and spinal cord and has a viscosity approximately that of water. It moves in an oscillatory manner, with zero net flow, in synchrony with intracranial blood pulsations. A detailed unde...

Upregulation of certain growth factors in the central nervous system can alter brain fluid dynamics. Hydrocephalus was produced in adult Sprague-Dawley rats by infusing recombinant basic fibroblast growth factor (FGF-2) at 1 microg/day into a lateral ventricle for 2, 3, 5, or 10-12 days. Lateral and third ventricular enlargement progressively increased from 2 to 10 days. Ventriculomegaly was al...

There is strong evidence that the composition of cerebrospinal fluid (CSF) influences brain development, neurogenesis, and behavior. The bidirectional exchange of CSF and interstitial fluid (ISF) across the ependymal and pia-glial membranes is required for these phenomena to occur. Because ISF surrounds the parenchymal compartment, neuroactive substances in the CSF and ISF can influence neurona...