Cefadroxil (Duricef, Mead Johnson and Company), resembles cephalexin and cephradine in spectrum of antibacterial activity but differs in human pharmacokinetic properties. Whether the latter are likely to affect activity in vivo was assessed by determining bactericidal activity against clinical isolates under conditions simulating the variation of drug concentration in the blood stream after an ...

Antibiotics are the most widely injudiciously used drugs for therapeutic purposes throughout world. This study aimed to detect cephalexin residue after discriminate and indiscriminate administration of antibiotic in broiler. Eighteen broiler chicks, DOC (Cobb-500) were collected & reared up 31 days. The chicks randomly divided into three groups namely control group (Group-A), (Group-B) (Gro...

background: in this study, we determine the vector competence of musca domestica with reference to the transmis­sion of susceptible and resistance bacterial strains in hospitals and slaughter house in sanandaj city, west iran. methods: totally 908 houseflies were collected to isolate bacteria from their external body based on standard proce­dures.antibiotic susceptibility testing was performed ...

purpose: to investigate the penetration of cefixime, cephalexin and ciprofloxacin into the human eye based on microbial inhibition by human aqueous samples after oral administration. method: sixty patients aged 40 to 75 years who were scheduled for cataract surgery were divided into three equal groups. one group received 500 mg oral ciprofloxacin 24, 12 and 2 hours preoperatively; another group...

In this study, a discriminative dissolution method was developed for Cephalexin OD (orally disintegrating) tablets 750mg. The solubility and stability of the cephalexin API was determined in ten different solutions. In that 0.01N HCl, glycine buffer pH 3-0, acetate buffer pH 4.5 and water gave good stability and the solubility. Dissolution profiling of cephalexin OD tablets 750mg of single batc...