Introduction Central venous pressure (CVP) is frequently used to guide fluid therapy, although there are confounders of CVP like intra-abdominal pressure (IAP) and mechanical ventilation. Despite a large number of studies on the interactions of intra-abdominal pressure, mechanical ventilation and CVP there are few studies investigating the impact of both major confounders of CVP in the same set...

Changes in central venous pressure were recorded continuously before, during and for 40 to 50 minutes after hemorrhage and transfusion in the amounts of 6.5 cc. per Kg. and 8.1 cc. per Kg. The pressures obtained 15 to 20 minutes after onset of blood volume changes were independent of the rate of hemorrhage or transfusion. In the average subject of 70 Kg., AP/AV for zero time was 0.7 cm. of wate...

Hemodynamic monitoring and optimization improve postoperative outcome during high-risk surgery. However, hemodynamic management practices among Chinese anesthesiologists are largely unknown. This study sought to evaluate the current intraoperative hemodynamic management practices for high-risk surgery patients in China. From September 2010 to November 2011, we surveyed anesthesiologists working...

BACKGROUND We tested the hypothesis that a common oscillatory pattern might characterize the rhythmic discharge of muscle sympathetic nerve activity (MSNA) and the spontaneous variability of heart rate and systolic arterial pressure (SAP) during a physiological increase of sympathetic activity induced by the head-up tilt maneuver. METHODS AND RESULTS Ten healthy subjects underwent continuous ...

Octreotide has been proposed for the treatment of variceal bleeding. The effects on portal pressure, however, have been variable in published studies. As bleeding is more directly related to pressure in the varices, this study investigated the effect on variceal pressure of octreotide and terlipressin, a vasoactive drug with a well established effect. Variceal pressure was measured during four ...

1. Practice advisory for perioperative visual loss associated with spine surgery: An updated report by the American Society of Anesthesiologists Task Force on Perioperative Visual Loss. ANESTHESIOLOGY 2012; 116:274 – 85 2. Marik PE, Baram M, Vahid B: Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares. Chest 2008; 134:172–...

BACKGROUND Patients in neurological critical care units often have lengthy stays that require extended vascular access and invasive hemodynamic monitoring. The traditional approach for these patients has relied heavily on central venous and pulmonary artery catheters. The aim of this study was to evaluate peripherally inserted central catheters as an alternative to central venous catheters in n...

Plasma osmolality alters control of sympathetic activity and heart rate in animal models; however, it is unknown whether physiological increases in plasma osmolality have such influences in humans and what effect concurrent changes in central venous and/or arterial pressures may have. We tested whether physiological increases in plasma osmolality (similar to those during exercise dehydration) a...

BACKGROUND Measurement of central venous pressure (CVP) is a reliable method for evaluating intravascular volume status and cardiac function; however it is an invasive and expensive method that may result in some complications such as arterial puncture, pneumothorax and development of infections. This study was performedto compare CVP measurements between central and peripheral catheters in inf...

The cornerstone of emergency management of sepsis is early, goal directed therapy, plus lung protective ventilation, broad spectrum antibiotics, and possibly activated protein C (Table 2). A randomized controlled trial was conducted in which patients with severe sepsis and septic shock received early, goal directed, protocol guided therapy during the first 6 hours after enrollment or the usual ...