A statistical design approach has been used to optimize the production of biomass by Cunninghamella sp. 2A1, evaluated based on lipidless biomass. A 2 3 full factorial central composite design (CCD) was chosen to study the combined effects of three factors; ammonium tartrate, peptone and glucose concentrations. The p-value for each factor was <0.05 suggesting that these factors have significant...

4-Androstenedione (AD), a 19-carbon steroid hormone is an oxidation product of phytosterol fermentation by Mycobacterium sp. The isolation of the product from the fermentation broth is a challenging task. Downstream processing is an important aspect of all biotechnological processes and has significant implications on quality and yield of the final product. In the present study, the statistical...

Biosorption of Acid Yellow (AY 17) and Acid Blue (AB 25) were investigated using a biomass obtained from brewery industrial waste spent brewery grains (SBG). A 2 full factorial response surface central composite design with seven replicates at the centre point and thus a total of 31 experiments were employed for experimental design and analysis of the results. The combined effect of time, pH, a...

The extraction of catfish (Clarias gariepinus) bone gelatin was optimized by using Response Surface Methodology (RSM) involving 4-factors, 5-levels Central Composite Design (CCD). The optimum conditions for extraction were produced by a pre-treatment of 3.35% HCl for 14.5 h along with hot water extraction at 67.23°C for 5.2 h. Results showed that the predicted yield by RSM (61.81%) was closely ...

Direct fermentation of 226 white rose tapioca stem to ethanol by Fusarium oxysporum was studied in a batch reactor. Fermentation of ethanol can be achieved by sequential pretreatment using dilute acid and dilute alkali solutions using 100 mesh tapioca stem particles. The quantitative effects of substrate concentration, pH and temperature on ethanol concentration were optimized using a full fact...

Response surface methodology was applied to optimize medium constituents for enzymatic production of L-cysteine from DL-2-amino-D-thiazoline-4-carboxylic acid (DL-ATC) by a novel Pseudomonas sp. Zjwp-14. With the Plackett-Burman design experiment, glycerol, DL-ATC, yeast extract, and pH were found to be the most powerful factors among the eight tested variables that influence intracellular enzy...

The present study deals with the immobilization of Aspergillus nidulans cellulase onto modified chitin (MC). The effect of contact time, cellulase concentration, MC dosage, temperature and agitation rate for maximum immobilization percentage and immobilization capacity is investigated on the basis of five-level-five-factor central composite design (CCD) obtained by response surface methodology ...

The goal of this study is to reduce the production cost of biodiesel, so we used non edible oil (castor seeds oil) which has a unique structure; suitable for biodiesel production and has lower cost compared to other biodiesel from other vegetable oils. Reactive extraction via ultrasonicassisted process was used offering the potential for shorter reaction times, cheaper reagents and less insigni...

A flexible printed circuit board (FPCB) is flexible, thin and lightweight; however, FPCBs experience more deflection and stress in the flow environment because of fluid–structure interaction (FSI), which affects their performance. Therefore, the present study focuses to optimize a typical FPCB electronic in order to minimize the deflection and stress induced in the system. In this study, numeri...

The continuous development of technology in automotive manufacturing process demands new solutions which is largely de-pendent on the development of lightweight, nonpollution for the environment materials of improved mechanical properties and also with a low cost production. According with these required characteristics of materials, the aims of this paper were to manufacturing Al-SiCp composit...