Although cell membranes are packed with proteins mingling with lipids, remarkably little is known about how proteins interact with lipids to carry out their function. Novel analytical tools are revealing the astounding diversity of lipids in membranes. The issue is now to understand the cellular functions of this complexity. In this Perspective, we focus on the interface of integral transmembra...

Coenzyme Q (CoQ) is a key component for many essential metabolic and antioxidant activities in cells mitochondria cell membranes. Mitochondrial dysfunction one of the hallmarks aging age-related diseases. Deprivation CoQ during can be cause or consequence this mitochondrial dysfunction. In any case, it seems clear that aging-associated deprivation accelerates these Non-genetic prolongevity inte...

Sphingolipids (SLs) are essential structural components of mammalian cell membranes. Our group recently determined that the oral anaerobe Porphyromonas gingivalis delivers its SLs to host cells and ability P. synthesize limits elicited inflammatory response during cellular infection.

Commercial Nafion membranes have been widely used for vanadium redox flow batteries (VRFB) but with relatively low ion selectivity. A chemical method is commonly employed to modify the organic membranes, whereas physical approaches are rarely reported in view of less compatibility species. In this study, an ultrathin polytetrafluoroethylene (PTFE) film than 30 nm deposited onto substrates by ra...

Herein, novel bioactive glass flakes (BGFs) (45S5 composition), obtained by compression in the liquid phase a stirred media mill, are combined with chitosan (CS) to develop composite membranes using solvent casting for guided bone regeneration (GBR). The incorporation of BGFs endows CS superior bioactivity as evidenced rapid hydroxyapatite formation after 3 days immersion simulated body fluid (...

Conventional proton exchange membrane fuel cells (PEMFCs) operate within narrow temperature ranges. Typically, they are run at either 80‒90 °C using fully humidified perfluorosulfonic acid membranes, or 140‒180 non-humidified phosphoric (PA)-doped to avoid water condensation-induced PA leaching. However, the ability function over a broader range of and humidity could simplify heat management, t...

Pulsed electric field-induced electroporation has been widely used, but its specific perforation theory not fully elucidated. Therefore, this Perspective paper takes as a clue the dynamic development relationship between pore energy and state in cell membranes. First, based on contribution of line tension, surface steric repulsion, applied field to energy, theoretical models reversible microsec...

Adenyl cyclase activity in mucous acinar cells and serous demilune cells of the rat sublingual gland was localized cytochemically. After incubation with adenylyl-imidodiphosphate (AMP-PNP) as substrate, deposits of reaction product are found along the cell membranes bordering the secretory surfaces of serous demilune cells. These are the membranes which participate directly in secretion by fus...