At the time of writing, five anti-CD19 CAR T-cell products are approved by U.S. Food and Drug Administration for seven different indications in lymphoid malignancies, including B-cell non-Hodgkin lymphoma, pediatric acute lymphoblastic leukemia, multiple myeloma. T cells chronic lymphocytic myeloid less common malignancies such as lymphomas Hodgkin lymphoma being tested early-phase clinical tri...

background: the clinical presentation of non-hodgkin lymphoma (nhl) varies tremendously depending upon the type of lymphoma and the areas of involvement. nhl can rarely present as an abdominal mass compressing the inferior vena cava. the clinical presentation due to obstruction of inferior vena cava has often been called the inferior vena cava syndrome (ivcs). it can present acutely or chronica...

Introduction: Primary gastric lymphoma (PGL) is a rare tumor, whose differential diagnosis may become complicated without precise immunohistochemistry (IHC) and genetic analysis. Case Presentation: A 33-year-old woman presented with gastric cancer and had undergone gastrectomy without precise IHC and staging in another center. Inappropriate IHC after surgery showed diffuse large B-cell lymphom...

b-cell lymphoblastic lymphoma (b-lbl) is an uncommon subtype of pediatric non-hodgkin lymphoma (nhl) which rarely involves the skin primarily. the positron emission tomography with 2-deoxy-2-[fluorine- 18] fluoro-d: -glucose integrated with computed tomography (18f-fdg pet/ct) scan findings of a 8-year-old boy with cutaneous b-lbl were presented. pet/ct scan demonstrated mild fdg uptake in the ...

abstract introduction connection of socioeconomic status measures (such as income and education and parental addiction) to childhood leukemia are likely to vary with place and time. the aim of this study was to assess the relation between socioeconomic status and childhood leukemia. materials and methods a case- control study conducted on 86 case of acute lymphoblastic leukemia age 0-14 years i...

Langerhans cell histiocytosis (LCH) is a rare neoplasm defined as the proliferation of bone marrow langerhans cells, which is a kind of dendritic cells. The major pathological features of LCH are expression of CD1a and S100 as well as Birbeck granules. Its presentation can differ from a mild bone lesion to a multi-systemic evolved malignant neoplasm; however, the latter outcome is almost rare. ...

Introduction: Primary gastric lymphoma (PGL) is a rare tumor, whose differential diagnosis may become complicated without precise immunohistochemistry (IHC) and genetic analysis. Case Presentation: A 33-year-old woman presented with gastric cancer and had undergone gastrectomy without precise IHC and staging in another center. Inappropriate IHC after surgery showed diffuse large B-cell lymphom...

background: expression of epstein-barr virus latent member protein-1 (ebv lmp-1) and loss of p16 protein expression are documented in lymphoma, indicating a relationship between them, but this relationship is not clear and sometimes contradictory. thus, this study was conducted to examine the relationship between the loss of p16 and ebv lmp-1 expression in jordanian patients diagnosed with lymp...

Background: Bovine leukaemia virus (BLV) is the primary cause of enzootic bovine leukaemia which belongs to the HTLV/BLV group of oncogenic retroviruses including Human T-cell leukaemia virus types 1, 2, and 3 and simian T-lymphotropic virus. Due to daily consumption of milk, meat and other dairy by-products, a possible role in appearing human cancers can be assumed for BLV. Materials and Metho...

Non-Hodgkin’s lymphoma is a heterogeneous malignancy originating from proliferation of lymphoid cells or their precursors. , we report a case of a 6-year-old Iranian male child admitted at the Department of Oral Medicine, School of Dentistry, Mashhad, Iran, in March 2019. The case was complaining about gingival swellings worsening for one month. Clinical and pathologic examination, comple...