Typhlitis, is also known as neutropenic enterocolitis, affects the cecum and distal ileum. It was frequently encountered in pediatricpatients who were undergoing treatment for leukemia. Nonetheless, it can affect adult patients, regardless of cause immunosuppression. We report case a 20-year-old patient receiving chemotherapy Osteosarcoma, had 6-day history nausea vomiting, fever sensation, dia...