Immunophenotyping of acute leukemia using flow cytometry after density gradient separation (dg-sep) of mononuclear cells is the international gold standard. But destroying red cells by whole blood lysis (wb-lysis) after direct staining has found a broad usage. Both methods revealed congruent results in phenotyping of 26 cases of acute myeloid leukemias by testing CD4, CD7, CD11b, CD11c, CD13, C...

Analysis of the blood smear, bone marrow aspiration, and bone marrow biopsy revealed the predomination of small lymphocytes, but 22% of the cells were blasts negative with cytochemical staining (Figure 1). Flow cytometric analysis showed two distinct populations: 65% of cells were small to moderate in size and CD19+, CD45+, CD5+, and CD20+/-, while 30% of cells were large, CD34+, CD13+, HLA DR+...

We report an uncommon case of Hodgkin's disease confined to the nasopharynx. An isolated polypoid mass of the nasopharynx was observed in a 41-year-old man presenting with increasing bilateral nasal obstruction. Histological study revealed a mixed cellularity type of Hodgkin's disease. Immunohistochemical analysis revealed CD30 and LMP1 expression and a lack of reactivity to CD15, CD3 and CD20....

A 50-year-old male presented with cough and breathlessness. A positron emissoin tomography scan revealed FDG (Fluorodeoxyglucose) avid mediastinal mass. Tru-cut biopsy showed fibrotic stromal tissue with cellular infiltrate consisting of abnormal lymphoid cells and few large cells with smudged nucleus. Immunohistochemistry revealed diffuse positivity with CD20, focal positivity for CD30 and rar...

  Chloroma or granulocytic sarcoma (GS) is a malignant neoplasm of myeloid lineage that occur in a variety of anatomic sites other than the bone marrow including soft tissue, bone, lymph node, nasal fossa, skin and sometime in the orbit. In the subconjunctiva it is rarely reported. A 4-year-old girl with a history of treated acute myelogenous leukemia was referred to Farabi Eye Hospital, Tehra...

Background: Ovarian cancer is the most common cause of cancer death worldwide. Incidence of ovarian cancer is more common in postmenopausal women. Premenopausal onset is rare and the present study described two cases of ovarian clear cell tumors in young women. Case Presentation: The patients presented with pelvic mass which was confirmed by sonography and laparotomy and final diagnosis was ...

Herein, we reported on a middle-aged woman presented with painless cervical lymphadenopathy. Past medical history was not significant. Pathologic examination of incisional biopsy show partial effacement of lymph node architecture with many reactive inflammatory cells admixed with Reed-Sternberg cells, many Charcot-Leyden crystals, and noncaseating granuloma. Immunohistochemical staining was pos...