Abstract Behavioral studies revealed that time perception is affected by the presence of a reward. Both experience and reward processing were shown to be distorted in major depressive disorder (MDD). We aimed investigate how neural correlates anticipation interact patients with MDD. Participants (17 healthy, seven MDD) performed task during fMRI scanning requires estimating speed moving rectang...

OBJECTIVE Recent studies of functional brain imaging have shown the involvement of the basal ganglia in executive processes such as planning and set-shifting. However, the specific contributions of the striatum in those processes remain unknown. This study aimed to test the hypothesis that the caudate nucleus is primarily involved in the preparation of a novel action and not in set-shifting per...

BACKGROUND The aim of this study was to determine age, gender, and hemispheric differences in the volume of the human neostriatum (striatum) nucleus in healthy humans. MATERIAL/METHODS This study was performed on 120 normal human subjects (60 males, 60 females, right-handed) 15-65 years old, divided into two groups: young (<40 yrs) and old (=≥40 yrs). Sectional brain images were obtained via ...

BACKGROUND Changes in the volume of the caudate nucleus over time in patients with schizophrenia has been shown to be directly related to neuroleptic exposure. Few studies have evaluated caudate volume in subjects with schizophrenia who were neuroleptic naive at intake and treated exclusively with atypical neuroleptics. METHODS Fourteen patients were matched by gender to 14 healthy controls a...