The self-assembly of dialkyl chain cationic surfactant dihexadecyldimethyl ammonium bromide, DHDAB, and nonionic surfactants monododecyl hexaethylene glycol, C(12)E(6), and monododecyl dodecaethylene glycol, C(12)E(12), mixtures has been studied using predominantly small-angle neutron scattering, SANS. The scattering data have been used to produce a detailed phase diagram for the two surfactant...

The structure of the lipoplex formed from DNA and the sugar-based cationic gemini surfactant 1, which exhibits excellent transfection efficiency, has been investigated in the pH range 8.8-3.0 utilizing small-angle X-ray scattering (SAXS) and cryo-electron microscopy (cryo-TEM). Uniquely, three well-defined morphologies of the lipoplex were observed upon gradual acidification: a lamellar phase, ...

Detergent sequestration using micelles as a hydrophobic sink for dissociated drug molecules is an established technique for determination of dissociation rates. The anionic surfactant molecules are generally assumed not to interact with the anionic DNA and thereby not to affect the rate of dissociation. By contrast, we here demonstrate that the surfactant molecules sodium dodecyl sulfate (SDS),...

The binary adsolubilization behaviors of 2-naphthol +biphenyl and 2-naphthol +1, 3-dichlorobenzene in a cationic fluorocarbon surfactant adsorbed layer formed on TiO2 have been investigated as a function of pH. In the binary adsolubilization of 2-naphthol+biphenyl, the adsolubilized amount of 2-naphthol increases gradually until pH 7 and then sharply with a further increase of pH, whereas the a...

Among different types of calixarenes, the water–soluble ones are of especial interest because of their possible applications in biochemical research. In order to elucidate the nature of aqueous solutions of a cationic amphiphilic calixarene, substituted tetrapropoxy-calix[4]arene bearing hydrophilic choline groups at the upper rim, we studied vis– spectroscopically the influence of the above sy...

Aim The aim of this work was to develop a novel vesicular carrier, ultradeformable liposomes (UDLs), to expand the applications of the Chinese herbal medicine, imperatorin (IMP), and increase its transdermal delivery. Methods In this study, we prepared IMP-loaded UDLs using the thin-film hydration method and evaluated their encapsulation efficiency, vesicle deformability, skin permeation, and...

Spectral studies on the interaction of acidic capsular polysaccharide (SPS), isolated from Klebsiella K28, with cationic dye and surfactants have been reported. The polymer induced strong metachromasy(~ 100 nm blue shift) in the cyanine dye pinacyanol bromide (PCYB). The SPS consists of D-glucose, D-galactose, D-mannose and D-glucuronic acid (2:1:2:1) molar ratio) in hexasaccharide repeating un...

In this paper, we report studies which aim to elucidate the mechanisms involved in the antimicrobial activity of three cationic lysine-based surfactants: LLM, LALM, and C6 (LL)2. To this end, a simple membrane model (i.e., 1,2-dipalmitoyl-sn-phosphatidylcholine, DPPC) was used to explore the monolayer properties at the air/liquid interface. Compression π-A isotherms of mixtures of DPPC/lysine s...

Spectral studies on the interaction of acidic capsular polysaccharide (SPS), isolated from Klebsiella K28, with cationic dye and surfactants have een reported. The polymer induced strong metachromasy (∼100 nm blue shift) in the cyanine dye pinacyanol bromide (PCYB). The SPS consists f d-glucose, d-galactose, d-mannose and d-glucuronic acid (2:1:2:1 molar ratio) in hexasaccharide repeating units...

of a dissertation by Ewelina Kalwarczyk A modern, twenty-first-century chemistry, not only continues the research conducted in previous centuries, but also brings together various branches of science and technology. The goal of this approach is usually to create new materials characterized by an interesting combination of physicochemical properties. In my studies, I followed this trend and appl...