PURPOSE We aimed to determine which antipsychotic is most effective for the treatment of acute schizophrenia with catatonic stupor. PATIENTS AND METHODS Data were obtained from the medical records of 450 patients with the diagnosis of schizophrenia, who had received acute psychiatric inpatient treatment between January 2008 and December 2010 at our hospital. Among them, 39 patients (8.7%) met...

Background: Recent literature has shown that a considerable percentage of patients with severe mental disorders can develop, over time, full-blown or subthreshold catatonia. Some studies corroborate the model an illness trajectory in which different would be arranged along continuum severity until development In such pathway, autistic traits (AT) and borderline personality disorder (BPD) may re...

A 67 year old lady with hypertension, type two diabetes mellitus, hypothyroidism, depression and deep vein thrombosis, independent in activities of daily living who was admitted one month history lethargy. She noted to have deterioration the living, complaining shortness breath.

BACKGROUND Malignant catatonia (MC) is a disorder consisting of catatonic symptoms, hyperthermia, autonomic instability, and altered mental status. Neuroleptic malignant syndrome (NMS) caused by antipsychotics is considered a variant of MC. Benzodiazepine (BZD) medications are safe and effective treatments providing rapid relief from MC. This case study reports a detailed clinical course of a c...

a substantial amount of evidence has proposed an important role for cyclooxygenase-2 (cox-2) enzyme in brain diseases and affiliate disorders. the purpose of this research was studying the effects of cox-2 selective inhibition on haloperidol-induced catatonia in an animal model of drug overdose and parkinson’s disease (pd). in this study, the effect of acute and sub-chronic oral administration ...