Vitex agnus-castus L. (chaste tree; chasteberry) is a popular herbal treatment, predominantly used for a range of female reproductive conditions in Anglo-American and European practice. The objective of this systematic review was to evaluate the evidence for the efficacy and safety of Vitex extracts from randomised, controlled trials investigating women's health.Eight databases were searched us...

AIM This study was designed to investigate the bioactive compounds in Costus afer Ker Gawl, an indigenous African medicinal plant whose leaf and stem extracts are used in the treatment of chronic inflammatory diseases, especially rheumatism and arthritis. MATERIALS AND METHODS The bioactive compounds present in the n-butanol fractions of C. afer leaf and stem were identified using qualitative...

Background. Cyclic mastalgia (CM) is premenstrual bilateral and diffuse breast pain that presents cyclically affects women in their reproductive years. It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on pituitary gland. Vitex agnus-castus (VAC) known for its dopaminergic activity possible actions CM hyperprolactinemia. However, treatment VAC...

Introduction: PCOS is an important reproductive and endocrine disorder in women in the reproductive age. Present reports indicate that Vitex agnus-castus acts through hypothalamus-pituitary axis. This study was carried out to evaluate the effects of Vitex fruit hydroalcoholic extract on the alteration of sex hormones in a PCOS animal model. Methods: Following 14 days of monitoring of estrous...

The current study examined the genotoxic effect of biosynthetic zinc oxide nanoparticles ZnONPs using Vitex agnus-castus plant, which contains effective compounds that inhibit growth pure cancer cells. phenotypic and structural characteristics biosynthesized were detected scanning electron microscopy (SEM). Most dense spherical with sizes ranging from (20-61) nanometers, on cervical cell line H...