OBJECTIVE Atherosclerotic large vessel disease is potentially involved in the pathogenesis of cerebral small vessel disease related to occurrence of white matter lesions (WMLs) in the brain. We aimed to assess morphological and functional carotid vessel wall properties in relation to WML using magnetic resonance imaging (MRI) in myocardial infarction (MI) patients. MATERIALS AND METHODS A tot...

Carotid artery occlusion is a major risk factor for ischemic stroke. Endovascular treatment of carotid artery occlusion in high-risk patients offers a therapeutic option to reduce subsequent ischemic events. The technical success and avoidance of complications of the endovascular recanalization of occluded carotid artery is contingent on proper visualization of the vessel wall. To highlight the...

BACKGROUND AND PURPOSE Converting enzyme inhibition and calcium blockade alter large arteries in hypertension. However, the heterogeneity of the response according to the site of cardiovascular measurements has never been investigated. METHODS In a double-blind study, we compared for 180 days 3 hypertensive patient groups treated with verapamil, trandolapril, or their combination. Using echo-...

during the past few years, researchers and practitioners have developed novel techniques, using ansa cervicalis to innervate muscles of the larynx paralyzed due to surgical procedures carried out in the chest and neck areas. during routine dissection of a middle-age male cadaver, an unusual course of the superior root of the ansa cervicalis was observed. in this case, the superior root of the a...

BACKGROUND Previous clinical studies have observed relationships between increased intima-media thickness (IMT) in the carotid artery, elevated blood pressure, and low wall shear stress (WSS) calculated from the Poiseuille equation. This study used numerical methods to more accurately determine WSS in the carotid artery and to investigate possible determinants of increased IMT. METHODS IMT [c...

Various mechanical phenomena are thought to contribute to the pathogenesis of atherosclerosis. Most finite-element analyses of arterial-wall mechanics to date have focused on the quantification of mechanical wall stresses, despite an abundance of experimental evidence suggesting that endothelial and smooth muscle cells readily respond to cyclic strain. In this study, we calculate the physiologi...

background common carotid artery (cca) ultrasound with measurement of intima-media thickness (imt) is a safe and noninvasive technique for assessing subclinical atherosclerosis and determining cardiovascular risks. moreover, the pattern of wall thickening in the brachial artery (ba) is rather diffuse compared to the carotid artery and may be a more sensitive indicator of long-term systemic expo...

BACKGROUND AND PURPOSE Parameters other than luminal narrowing are needed to predict the risk of stroke more reliably, particularly in patients with <70% stenosis. The goal of our study was to identify clinical risk factors and CT features of carotid atherosclerotic plaques, in a retrospective cohort of patients free of stroke at baseline, that are independent predictors of incident stroke on f...

BACKGROUND AND PURPOSE Although studies have evaluated the differential imaging of moyamoya disease and atherosclerosis, none have investigated the added value of vessel wall magnetic resonance imaging (MRI). This study evaluates the added diagnostic value of vessel wall MRI in differentiating moyamoya disease, atherosclerotic-moyamoya syndrome (A-MMS), and vasculitic-MMS (V-MMS) with a multico...

High-resolution MRI may be used to monitor the progression of human carotid atherosclerosis by measuring the lumen and wall area changes over time. The purpose of this study was to analyze the precision of quantitative measurements of lumen and wall areas. Two independent MR scans near the carotid bifurcation were conducted on eight patients within 2 weeks. The error of lumen area measurement w...