background patients with systemic lupus erythematous (sle) are more prone to atherosclerosis and cardiovascular diseases due to atherosclerosis and consequently death. objectives the aim of this study was to explore a possible relationship between the intima media thickness (imt) of carotid arteries and the levels of c-reactive protein (crp) in sle patients. patients and methods: sixty sle pati...

BACKGROUND Carotid arterial intima-media thickness is used as a noninvasive surrogate end point to measure progression of atherosclerosis, but its relation to coronary events has not been fully explored. OBJECTIVE To determine whether carotid arterial intima-media thickness predicts coronary events. DESIGN Long-term follow-up (average, 8.8 years) of a previously assembled cohort of persons ...

BACKGROUND Physical activity reduces the risk of vascular disease. This benefit is not entirely explained through an effect on vascular risk factors. We examined the relationship of physical activity and characteristics of the carotid artery wall in patients with vascular disease or risk factors. METHODS AND RESULTS Cross-sectional analyses were performed in 9578 patients from the SMART (Seco...

BACKGROUND AND PURPOSE MR imaging-detected carotid intraplaque hemorrhage indicates vulnerable plaque with high stroke risk. Angiotensin II stimulates intraplaque hemorrhage in animal models, and the angiotensin system is highly regulated by vitamin D. Our purpose was to determine whether low vitamin D levels predict carotid intraplaque hemorrhage in humans. MATERIALS AND METHODS In this cros...

BACKGROUND AND PURPOSE The purpose of this study was to investigate whether the Framingham Cardiovascular Risk Profile and carotid artery intima-media thickness are associated with cortical volume and thickness. METHODS Consecutive subjects participating in a prospective cohort study of aging and mild cognitive impairment enriched for vascular risk factors for atherosclerosis underwent struct...

Carotid ultrasound measurement of carotid intima-media thickness (CIMT) and detection of plaques is a useful method to better assess cardiovascular disease risk status, especially in those at intermediate risk. We discuss the use CIMT and other emerging techniques such as contrast-enhanced carotid ultrasound imaging in the evaluation of the carotid artery and its value in cardiovascular disease.

OBJECTIVE To investigate prospectively whether subclinical vascular disease is associated with future depressive symptoms in the elderly. APPROACH AND RESULTS A multicenter cohort of community-dwelling individuals aged 65 to 85 years was examined for carotid plaque presence and common carotid artery intima-media thickness at baseline and followed up after 2, 4, 7, and 10 years. At baseline an...

Carotid ultrasound is an imaging modality that allows non-invasive assessment of vascular anatomy and function. Carotid intima-media thickness (IMT) has been shown to predict cardiovascular (CV) risk in multiple large studies. However, in 2013, American College of Cardiology/American Heart Association guidelines designated that the carotid IMT as class III evidence level was not recommended for...

OBJECTIVES To detect the correlation between high-sensitivity-CRP, carotid plaque, neurological function and intima-media thickness, and help physicians in the diagnosis of atherosclerotic cerebral infarction. METHODS A total of 96 patients with the first onset of atherosclerotic cerebral infarction were included in the study from July 2013 to May 2015. The test of high-sensitivity-CRP, exami...