In Germany, caries of young people has been declining since the late 1980s, while the prevalence of early childhood caries has remained steady. Data from a number of regional studies suggest a current prevalence between 10% and 15%. However, there is a dearth of longitudinal observational study data on the risk of caries in the permanent teeth of persons who as children had to undergo comprehen...

UNLABELLED Glucosyltransferase B is an enzyme produced by Streptococcus mutans, which catalyzes synthesis from sucrose of insoluble glucans that provide support to the biofilm. It is one of the main virulence factors in the generation of dental caries. However, its role is unclear in caries-free individuals who carry the bacteria. The aim of this study was to determine the production of glucosy...

Streptococcus mutans present in a man on a world wide basis (Birgitta Kohler & Douglas Bratthall 1976). High numbers in the mouth of Streptococcus mutans are associated with both high prevalence and a high incidence of dental caries. The Directorate of Oral Health Ministry of Health Republic of Indonesia declared 60 80 percent of school children between 4 14 years by age were suffering from den...

Background: Saliva is a complex mixture of fluids which regulates oral health. Studies have stated that calcium and phosphorous content of saliva is low in caries active persons. But most investigators have been unable to confirm this finding .This is attributed to the interplay of other factors including proteins and enzymes. Thus levels and state of calcium and phosphorous in saliva may be an...

introduction: it was to compare the efficacy of semiannually fluoride varnish application versus pit and fissure sealant to reduce occlusal caries incidence. materials and methods: a randomized parallel designed study was conducted with 352 child-ren aged 6-7 years. participants were allocated into biannual application of varnish (n=179) (naf 5 %( durafluor, dentsply®, latin america) or resin-b...

BACKGROUND Dental caries is a major problem in preschool children. The contribution of saliva in providing defense during caries process is of primary importance. pH buffer capacity through bicarbonate, phosphate and protein buffer systems have universal acceptance as a caries defense mechanism. Antioxidant capacity of saliva can constitute a first line of defense against chronic degenerative d...

Abstract Background "Core microbes" play a key role in the development of caries and lead to microbial disorders. Our goal was detect core microbes associated with microbiota imbalance early childhood (ECC). Methods Fifteen caries-free children fifteen high-caries (DMFT ≥ 10) aged 4–6 years old were recruited according diagnostic criteria suggested by WHO. The 16S rRNA genes from samples plaque...

There are universal patterns of caries, in terms of prevalence, incidence, frequency distribution and rates of progression, in permanent teeth that can be considered working rules that can be applied when planning dental care. The universal patterns are: (1) caries levels follow trend lines; therefore, knowing the caries level at one age can be used to predict the levels at later ages in that c...