An increasing interest in applying synthetic biology techniques to program outer membrane vesicles (OMV) are leading to some very interesting and unique applications for OMV where traditional nanoparticles are proving too difficult to synthesize. To date, all Gram-negative bacteria have been shown to produce OMV demonstrating packaging of a variety of cargo that includes small molecules, peptid...

The proximal tubule (PT) reabsorbs the majority of sodium, bicarbonate, and chloride ions, phosphate, glucose, water, and plasma proteins from the glomerular filtrate. Despite the critical importance of endocytosis for PT cell (PTC) function, the organization of the endocytic pathway in these cells remains poorly understood. We have used immunofluorescence and live-cell imaging to dissect the i...

Since the introduction of the maritime container in the mid 1950's, liner shipping groups have migrated from inefficient traditional cargo handling techniques to large cellular vessels which can be seen at any of the world's major ports today. The use of the container improved intermodal productivity and allows for shorter point to point transit times. In addition, cargo damage is reduced. On o...

We evaluated 10 years of reported hazardous cargo incident information from the U.S. Air Force and Naval Safety Centers. In this first of two papers describing the hazardous cargo problems reported by the two services, we describe types of aircraft and types of hazardous cargo involved in incidents not causing aircraft mishaps. Normally, hazardous cargo must be manifested as such and no passeng...

The presented paper addresses the problem of detecting and tracking moving objects for autonomous cargo handling in port terminals using a perception system which input data is a single layer laser scanner. A computationally low cost and robust Detection and Tracking Moving Objects (DATMO) algorithm is presented to be used in autonomous guided vehicles and autonomous trucks for efficient transp...

This paper provides a status report on the progress of improving small-scale combat in Wargus. The main goal of the project was to automatically learn complex tactics through Monte Carlo strategies. Monte Carlo strategies can be used as a game tree search method and provide a mechanism for handling the uncertainty and search complexity in an RTS game. The idea to explore Monte Carlo search as a...

This paper examines the changing business environment for ocean carriers and ports in terms of the new technologies that might be adopted in the period 2000–2010. It opens with a discussion of the two key supply segments, liner and tramp shipping, and explores their nature and how they have evolved since World War II. Issues like economies of scale and new technology adoption are discussed, pav...

Autophagy is a process delivering cytoplasmic components to lysosomes for degradation. Autophagy may, however, play a role in unconventional secretion of leaderless cytosolic proteins. How secretory autophagy diverges from degradative autophagy remains unclear. Here we show that in response to lysosomal damage, the prototypical cytosolic secretory autophagy cargo IL-1β is recognized by speciali...

Speed economy, proposed by Japanese scholars Masaki Tamura, refers to get the cost savings flow by accelerating the transaction process [1], which brings the a large market space to the cargo/express delivery industry [2]. Due to the rapidly growth of China air cargo/express market and the ongoing increasingly opening up of the sky, international cargo/express giants have set up their hubs in C...

An international study of the airport choice factors for non-integrated cargo airlines By John Gardiner Recent forecasts predict that the current number of all-cargo aircraft worldwide will more than double over the next 20 years, spurred on by trends such as reduced passenger belly hold capacity on short and medium haul routes and a growing recognition of the profit potential of cargo by airli...